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Selected Publications

2006

  • William H. Yong, Pramod V. Butte, Brian K. Pikul, Javier A. Jo, Qiyin Fang, Thanassis Papaioannou, Keith L. Black, and Laura Marcu, "Distinction of brain tissue, low grade and high grade glioma with time-resolved fluorescence spectroscopy," Frontiers in Bioscience Vol. 11, 1255-1263, May 1, 2006 [PDF]
2005
  • J. A. Jo, Q. Fang, T. Papaioannou, J. Qiao, M. C. Fishbein, A. Dorafshar, T. Reil, D. Baker, J. Freischlag, L. Marcu, "Laguerre Based Method for Analysis of Time-Resolved Fluorescence Data: Application to In-Vivo Characterization and Diagnosis of Atherosclerotic Lesions," Submitted to Journal of Biomedical Optics (July 2005). [PDF]
  • J. A. Jo, Q. Fang, T. Papaioannou, L. Marcu, "Ultra-fast method for the analysis of fluorescence lifetime imaging microscopy based on the laguerre expansion technique," Accepted for publication in IEEE Journal of Selected Topics in Quantum Electronics and Biophotonics (August 2005). [PDF]
  • Laura Marcu, Qiyin Fang, Javier A. Jo, Thanassis Papaioannou, Amir Dorafshar, Todd Reil, Jian-Hua Qiao, J. Dennis Baker, Julie A. Freischlag and Michael C. Fishbein, "In vivo detection of macrophages in a rabbit atherosclerotic model by time-resolved laser-induced fluorescence spectroscopy," Atherosclerosis, Vol. 181(2): 295-303, 2005. [PDF]
  • O. V. Ivanova, L. Marcu, M. C. K. Khoo, "Nonparametric recognition of fluorescent system for tissue characterization: Simultaneous deconvolution in wavelength and time dimensions," Annals of Biomedical Engineering, 33(4): 531-544, 2005. [PDF]
2004
  • P. T. Vernier, Y. Sun, L. Marcu, C. M. Craft, and M. A. Gundersen. "Nanosecond Pulsed Electric Fields Perturb Membrane Phospholipids in T Lymphoblasts," FEBS Letters, 572(1): 103-108, 2004. [PDF]
  • P. T. Vernier, M. Thu, L. Marcu, C. M. Craft, and M. A. Gundersen. "Nanosecond Electroperturbation-mammalian cell selectivity and bacterial spore resistance," IEEE Transactions on Plasma Science, 32(4): 1620-1625, 2004. [PDF]
  • P. Thomas Vernier, Yinghua Sun , Laura Marcu, Cheryl M. Craft, and Martin A. Gundersen, "Nanoelectropulse-Induced Phosphatidylserine Translocation," Biophysical Journal, Vol.86(6):4040-4048, 2004. [PDF]
  • Laura Marcu, Javier A. Jo, Pramod V. Butte, William H. Yong, Brian K. Pikul, Keith L. Black, Reid C. Thompson, "Fluorescence lifetime spectroscopy of glioblastoma multiforme," Photochemistry and Photobiology, 80:98-103, 2004. [PDF]
  • Qiyin Fang, Thanassis Papaioannou, Javier A. Jo, Russel Vaitha, Kumar Shastry and Laura Marcu, "Time-domain laser-induced fluorescence spectroscopy apparatus for clinical diagnostics," Review of Scientific Instruments, Vol. 75(1):151-162, 2004.
    [PDF]
  • Javier A. Jo, Qiyin Fang, Thanassis Papaioannou and Laura Marcu, "Fast model-free deconvolution of fluorescence decay for analysis of biological systems," Journal of Biomedical Optics, Vol. 9(4):743-752, 2004.
    [PDF]
  • T. Papaioannou, N. Preyer, Q. Fang, M. Carnohan, R. Ross, A. Brightwell, G. Cottone, L. Jones and L. Marcu, "Effects of fiber-optic probe design and probe-to-target distance on diffuse reflectance measurements of turbid media: an experimental and computational study at 337 nm," Applied Optics, Vol. 43(14):2846-2869, 2004. [PDF]
  • P. Ashjian, A. Elbarbary, P. Zuk, D. A. DeUgarte, P. Benhaim, M. H. Hedrick and L. Marcu, "Noninvasive in-situ evaluation of osteogenic differentiation by time-resolved laser-induced fluorescence spectroscopy," Tissue Engineering, Vol. 10(3/4):411-420, 2004. [PDF]
2003
  • P. T. Vernier, A. Li, L. Marcu, C. M. Craft and M. A. Gundersen, "Ultrashort pulsed electric fields induce membrane phospholipid translocation and caspase activation: differential sensitivities of Jurkat T lymphoblasts and rat glioma c6 cells," IEEE Transactions on Dielectrics and Electrical Insulation, Vol. 10(5):795-809, 2003.
    [PDF]
  • P. Thomas Vernier, Yinghua Sun, Laura Marcu, Sarah Salemi, Cheryl M. Craft and Martin A. Gundersen, "Calcium burst induced by nanosecond electric pulses," Biochemical and Biophysical Research Communications, Vol. 310(2): 286-295, 2003. [PDF]
  • M. Behrend, A. Kuthi, X. Gu, P. T. Vernier, L. Marcu, C. M. Craft, and M. A. Gundersen, "Pulse generators for pulsed electric field exposure of biological cells and tissues," IEEE Transactions on Dielectrics and Electrical Insulation, Vol.10:820-825, 2003. [PDF]
1999-2002
  • L. Marcu, M. C. Fishbein, J. M. Maarek, W. S. Grundfest, "Discrimination of lipid-rich atherosclerotic lesions of human coronary artery by time-resolved laser-induced fluorescence spectroscopy," Atheroscler Thromb Vasc Biol. 21:1244-1250, 2001. [PDF]
  • J. M. Maarek, L. Marcu, M. Fishbein, W. S. Grundfest, "Time-resolved fluorescence of aortic wall: use for improved identification of atherosclerotic lesions," Lasers in Surgery and Medicine, 27:241-254, 2000 [PDF]
  • J. M. Maarek, L. Marcu, W. J. Snyder, W. S. Grundfest, "Time-resolved fluorescence spectra of arterial fluorescent compounds reconstruction with Laguerre expansion technique." Photochemistry and Photobiology 71:178-187, 2000. [PDF]
  • L. Marcu, W. S. Grundfest, J. M. Maarek, "Photobleaching of arterial fluorescent compounds: characterization of elastin, collagen, and cholesterol time-resolved spectra during prolonged ultraviolet irradiation", Photochemistry and Photobiology 69:713-721, 1999. [PDF]

 
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