Clinical Scholars Program
This innovative program will provide funding, career guidance, education and skill acquisition for aspiring clinical scientists working at the Medical Center.
Essential Elements of the Program
- The program is directed towards residents (in the later years of their training), fellows, and young faculty with aspirations to become clinical scientists.
- All training programs and clinical departments are eligible to nominate candidates for competitive admission.
- Program duration of 2 years: Year 1: part-time curriculum in translational medicine and clinical research; Year 2: full-time research under the supervision of an experienced mentor. In special cases, admission for a one year program, which combines fulltime research with participation in the curriculum, may be considered.
- Potential funding for up to one year of full-time research for those judged to be most competitive for future funding.
- Required plan for a K award or other grant from NIH to be tabled during the first year with application for funding to be awarded during research year.
- The principal criterion for a successful outcome is the production of a successful clinical scientist who will have an impact on a field of clinical science upon graduating from the program.
- The essential requirement for defining a successful outcome will be a successful application for peer-reviewed research support, particularly a K-series grant from NIH.
- Competitiveness in the job market would also be a goal of the program. This would be assessed by the following:
- Research publications
- Grant support
- Likelihood of future grant support based upon current work
- Presentation and communication skills
- Breadth of scientific understanding
- Entrepreneurial approach
- Specific personal qualities and skills will be developed while in the program:
- Dedication to solving a scientific problem
- Ability to formulate a hypothesis or relevant research question
- Ability to present information to others
- Ability to review basic and clinical research critically
- Appreciation of the relevance of a broad range of scientific disciplines
Ongoing Career Development at Cedars-Sinai Medical Center
Clinical scholars who excel will be viewed as potential faculty recruits. Appropriate discussions will be initiated with such individuals to ascertain whether their career goals can be served by a faculty appointment at Cedars-Sinai, including considerations of start-up support for an independent research career.
|ISSUES IN CLINICAL AND TRANSLATIONAL RESEARCH||BIOSTATISTICS/SPECIAL TOPICS|
|Design of epidemiologic studies||Biostatistics - Confounding, bias, study design|
|Testing a hypothsis; asking a good question||Biostatistics - (finish study design) - Descriptive statistics for continuous data|
|Design of clinical trials||Biostatistics - Descriptive statistics for binary and survival data|
|Measures and how they influence data analysis: Categorical measures||Biostatistics - Elementary probability theory & distributions - Normal distribution|
|Measures and how they influence data analysis: Continuous measures||Biostatistics - Central limit theorem & confidence intervals|
|Randomization, sample size and power||Biostatistics - Hypothesis testing & equivalence testing|
|Data collection, recording, storage and management||Biostatistics - Power, sample size, incomplete (missing) data|
|Questionnaire design and psychometrics||Biostatistics - Correlation, bivariate and multiple regression - an introduction|
|Data and Safety Monitoring||Biostatistics - Comparing means - t tests and analysis of variance|
|Bioinformatics and information system for clinical research||Biostatistics - Binary outcomes - comparing proportions - chi square tests|
|Good Clinical Practices (GCP)||Biostatistics - Statistical reporting in scientific papers - wrap up & review|
|Clinical Trial Management|
|FDA and ICH Regulations for Drugs and Devices|
|Introduction to Grantsmanship||Intro to Bayesian statistics|
|How the NIH review process works||Biostatistics 'consulting'|
|Grant writing - putting together a proposal|
|Budgeting for your study||Animal Imaging Technologies|
|Surviving and thriving in the grants game - Real life stories||Microscopy & Image Analysis|
|Non-NIH sources: Foundations, pharmaceutical and industrial support for research||Microarray Technology & Analysis|
|Scientific writing and publishing||From a Basic Discovery to Clinical Trial|
|Networking and collaborations in Science||Stem Cells|
|Scientific conduct||Stem Cells Applications and the Heart|
|Ethics in Human Subjects research|
|Issues in Animal Research|
|Managing a laboratory/research team|
|Interacting with the public and the media|
|Entrepeneurship in Science|
|Pharmaceutical clinical trials|
|Stem Cell Applications and the Liver|
- The curriculum is designed to allow busy clinicians to participate with minimal disruption of their duties. Some of the sessions are optional.
- Teaching sessions will be held from 5-6:30 twice weekly (Tuesdays and Thursdays) in the Davis Building, Classroom 1004; full participation is expected. These classes are taken with the Graduate students. Tuesday Class - "Issues in Clinical & Translational Research" Thursday Class - "Biostatistics"
- Special Events will include gatherings of all clinical scholars for lectures by distinguished clinical scientists, brief research-in-progress seminars by clinical scholars, and other special seminars..
- Basic Science Liaison. Clinical scholars will have an assigned basic science mentor where it is deemed to be useful. Attendance at the laboratory meetings of the mentor would allow the scholar to understand better the language of science and to interact with scientists in a related discipline.
- Grant Writing Workshops. These will be conducted as one-to-one encounters with a member of the Research Grant Development Team. The goal is to generate a real application for peer-reviewed funding within an assigned period of time.
Dr. Leon G. Fine
Professor of Biomedical Sciences and Medicine
Chair, Cedars-Sinai Department of Biomedical Sciences
Director of Graduate Research Education
Phone: (310) 423-6457
Emma Yates Casler
Phone: (310) 423-8294