The disorder starts with cramps and weakness in the hands and sometimes the feet. Weakness may attack on one side of the body more than the other. As time goes by, the muscles may tighten, which can lead to tremors and spasms. Patients eventually experience difficulty swallowing and breathing.
Causes and Risk Factors
In many instances, the cause of ALS is unknown. An inherited tendency to these disorders appears to be involved about 10 percent of cases. More men than women get this disease.