Conditions and Treatments

Rheumatic diseases are chronic diseases that affect the skin, bones, joint structures and muscles, usually causing inflammation and pain. Although rheumatic diseases take many forms, many have a common origin: the body's immune system mistakes its own cells for harmful foreign agents and attacks them.


(Click on the image* to enlarge.)

To understand how inflammation and pain occur in a joint, it's important to understand how our joints and muscles work together to give us the ability to move - from picking up a pencil to dancing and from walking to nodding our heads. Every joint is made up of:

  • Bones
  • Cartilage - a smooth, white, shock-absorbing layer that caps each bone to allow it to move smooth against the other bone or bones in the joint
  • Synovial membrane - provides lubrication for the joint
  • Ligaments - strong fibers that attach one bone to another, keeping the joint stable, supported and properly aligned
  • Tendons - attach muscles to bones either above or below the joint

Some joints also have fluid-filled sacs (bursae) between the muscles, tendons and bones. Bursae are designed to reduce the friction that occurs when the bones, muscles and tendons move. Each bursa is lined with a synovial membrane, which releases lubricating fluid.

Cedars-Sinai's Rheumatology Services offers comprehensive treatments, including:


*Reprinted from Rheumatology, 3rd Edition. Peter A. Simkin. "The Musculoskeletal System," pg. 58. 2003, with permission from Elsevier.
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