Andrew Li, MD
|Assistant Professor, OBGYN|
Awards and Activities
|Clinical Scholar's Award: American Association of Cancer Research||2002|
|Scholar-in-Training Award: American Association of Cancer Research||2001|
|Reviewer: Obstetrics and Gynecology||Current|
|Reviewer: Clinical Cancer Research||Current|
|Reviewer: American Journal of Obstetrics and Gynecology||Current|
|Reviewer: Cancer Research||Current|
|Reviewer: Gynecologic Oncology||Current|
|Fellow: American College of Obstetrics and Gynecology||1995|
|Member: American Association for Cancer Research||1999|
|Full Member: Society of Gynecologic Oncologists||1999|
Influence of molecular and lifestyle factors on epithelial ovarian cancer biology. Specifically, examining the influence of obesity, statin use, and cigarette smoking on survival, and also studying molecular mechanisms in aberrant androgen receptor signaling in malignant ovarian cell cultures.
Established the interaction between androgen receptor polymorphisms and epidermal growth factor receptor signaling in ovarian cancers; identified significant correlations between obesity and statin use as factors in ovarian cancer survival.
Current investigations include:
Determining the molecular mechanisms by which statins influence aggressive ovarian cancer biology.
- Pavelka JC, Brown RS, Karlan BY, Cass I, Leuchter RS, Lagasse LD, Li AJ: Effect of obesity on survival in epithelial ovarian cancer. Cancer, 107(7): 1520-4, 2006
- Li AJ, Scoles DR, Armstrong KU, Karlan BY: Androgen receptor cytosine-adenine-guanine repeat polymorphisms modulate EGFR signaling in epithelial ovarian carcinomas. Gynecol. Oncol., 109(2): 220-5, 2008
- Li AJ, Karlan BY: Androgen mediation of thrombocytosis in epithelial ovarian cancer biology. Clin. Cancer Res., 11(22): 8015-8, 2005
- Li AJ, Elmore RG, Pavelka JC, Karlan BY: Hyperandrogenism, mediated by obesity and receptor polymorphisms, promotes aggressive epithelial ovarian cancer biology. Gynecol. Oncol., 107(3): 420-3, 2007
- Li AJ, Lerner DL, Gapuzan ME, Karlan BY: AIB1 polymorphisms predict aggressive ovarian cancer phenotype. Cancer Epidemiol. Biomarkers Prev., 14(12): 2919-22, 2005
- Li AJ, Baldwin RL, Karlan BY: Short androgen receptor allele length is a poor prognostic factor in epithelial ovarian carcinoma. Clin. Cancer Res., 9(10 Pt 1): 3667-73, 2003