Eric Ley

Director, Surgical Intensive Care Unit, General Surgery

Academic Appointments

Associate Professor, Surgery

Awards and Activities

Circle of Friends, Cedars-Sinai Medical Center2011
Journal of Trauma Management and OutcomesCurrent
American College of Surgeons2000
Association of Academic Surgeons2012
American Association for the Surgery of Trauma 2013

Research Focus

Novel treatments for traumatic brain injury, including beta-adrenergic receptor inhibitors, anti-inflammatory strategies, and antioxidants. Traumatic brain injury's connection to other diseases such as amyotrophic lateral sclerosis and Alzheimer's.

Research Contributions

Characterization and inhibition of interaction between EphB4 receptor tyrosine kinase and the EphrinB2 ligand, demonstrating angiogenic potential. Novel imaging of cerebral glucose metabolism after traumatic brain injury. Leader in treatment of traumatic brain injury using beta-adrenergic inhibitors.

Current investigations include:

Immunological cascade after trauma. Beta adrenergic receptors and traumatic brain injury. Resuscitation after trauma. Human factors to improve health care safety and efficiency.

Selected Publications

  1. Liou DZ, Barmparas G, Ley EJ, Salim A, Tareen A, Casas T, Lee D, Bukur M: To swab or not to swab? A prospective analysis of 341 SICU VRE screens. J Trauma Acute Care Surg, 76(5): 1192-200, 2014
  2. Berry C, Ley EJ, Margulies DR, Pruett J, Miller C, Bukur M, Palestrant D, Malinoski D, Salim A: Prospective evaluation of posttraumatic vasospasm: determining its clinical significance after traumatic brain injury. Am Surg, 80(3): 310-2, 2014
  3. Singer MB, Ley EJ: Re: Insurance- and race-based disparities decrease in elderly trauma patients. J Trauma Acute Care Surg, 75(2): 347, 2013
  4. Ley EJ, Short SS, Liou DZ, Singer MB, Mirocha J, Melo N, Bukur M, Salim A: Gender impacts mortality after traumatic brain injury in teenagers. J Trauma Acute Care Surg, 75(4): 682-6, 2013
  5. Liou DZ, Warren H, Maher DP, Soukiasian HJ, Melo N, Salim A, Ley EJ: Midodrine: a novel therapeutic for refractory chylothorax. Chest, 144(3): 1055-7, 2013
  6. Salim A, Ley EJ, Berry C, Schulman D, Navarro S, Zheng L, Chan LS: Increasing organ donation in Hispanic Americans: the role of media and other community outreach efforts. JAMA Surg, 149(1): 71-6, 2014

Lab Information

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