Jayoung Kim, PhD

Research Scientist, Biomedical Sciences

Research Scientist, General Surgery

Phone:(310) 423-7168

Academic Appointments

Associate Professor, Surgery
Associate Professor, Biomedical Sciences
Assistant Professor, Medicine

Awards and Activities

DREAM NO IC Scholar, Interstitial Cystitis Association (ICA)2014
Interstitial Cystitis Association Pilot Research Program Award2011 - 2012
Eleanor and Miles Shore Scholar2009 - 2011
Edwin Beer Scholar Award2008 - 2010
Fishbein Family IC Research Foundation Scholarship2008
American Foundation for Urological Disease Research Scholar 2004
Winner of the Young Scientists Academic Fund1995 - 1999
American Association of Cancer Research (AACR) Active member2003
American Urological Association (AUA), Active member2003
President,New England BioScience Society (NEBS), Elected by the membership2005 - 2006
Society for Basic Urological Research (SBUR) Active member2006
Society of Urodynamics, Female Pelvic Medicine, Urogenital Reconstruction (SUFU)2013
International Society for Computational Biology (ISCB)2014
PRMRP Pre-IC peer review panel, Department of Defense2014
Human Proteome Organization (HUPO)2014

Research Focus

Molecular studies of genitourinary tract pathophysiology focused on molecular mechanism of prostate and bladder cancer metastasis, and biomarker discovery for interstitial cystitis/chronic pelvic pain syndrome (IC/CPPS) diagnosis

Current investigations include:

Non-invasive biomarker discovery for IC diagnosis
Understanding of microbiota and proteome of IC
Identification of predictive gene set for chemoresistant bladder cancer

Selected Publications

  1. Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J: Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment. Proteomics, , 2014
  2. You S, Yang W, Anger JT, Freeman MR, Kim J: 'Omics' approaches to understanding interstitial cystitis/painful bladder syndrome/bladder pain syndrome. Int Neurourol J, 16(4): 159-68, 2012
  3. Yang W, Chung YG, Kim Y, Kim TK, Keay SK, Zhang CO, Ji M, Hwang D, Kim KP, Steen H, Freeman MR, Kim J: Quantitative proteomics identifies a beta-catenin network as an element of the signaling response to Frizzled-8 protein-related antiproliferative factor. Mol. Cell Proteomics, 10(6): M110.007492, 2011
  4. Kim J, Morley S, Le M, Bedoret D, Umetsu DT, Di Vizio D, Freeman MR: Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells: potential effects on the tumor microenvironment. Cancer Biol. Ther., 15(4): 409-18, 2014
  5. Kim J, Keay SK, You S, Loda M, Freeman MR: A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2. PLoS ONE, 7(12): e50392, 2012
  6. Kim J, Di Vizio D, Kim TK, Kim J, Kim M, Pelton K, Clinton SK, Hai T, Hwang D, Solomon KR, Freeman MR: The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing network. PLoS ONE, 7(7): e39448, 2012

Lab Information