Margareta Pisarska, MD

Director, Reproductive Endocrinology & Infertility
Fax:(310) 423-0140

Academic Appointments

Associate Professor, Obstetrics and Gynecology
Associate Professor, OBGYN

Awards and Activities

Third Annual Cedars-Sinai Research Day Poster Award, 2012
Endocrinology, features in 2011
Office of Research on Women's Health (ORWH) REAP Award2006
ACOG-ORTHO Academic Training Fellowship1997 - 1998
Herbert S. Kupperman Award 1996
Advisory Medical Board Member2004 - 2007
Editor: ASRM News2001 - 2009
Medical Editor: (Johnson & Johnson) Infertility DivisionCurrent
Society of Reproductive Endocrinology and Infertility1996
American Society for Reproductive Medicine1996
The Endocrine Society2000
Society for Gynecologic Investigation2005
American Board of Obstetrics and Gynecology2009
Los Angeles OB/Gyn Society 2011
American Board of Obstetrics and Gynecology2011

Research Focus

Investigating transcriptional regulation in the ovary. Interested in regulation of certain transcription factors and how they relate to follicle/egg development and premature loss and subsequent infertility. Currently looking at FOXL2, a transcription factor associated with premature ovarian failure.
In addition,conducting work on the genetics and outcomes of pregnancies conceived from couples with infertility including those conceived through in vitro fertilization.

Research Contributions

Research has contributed to understanding ovarian physiology.
Identification of changes in early implantation

Current investigations include:

Transcriptional regulation in the ovary. Transcriptional regulation of follicle/egg development with premature loss and subsequent infertility. Forkhead family of transcription factors. Genetics and outcomes of pregnancies conceived from couples with infertility including those conceived through in vitro fertilization.

Selected Publications

  1. Huang A, Adusumalli J, Patel S, Liem J, Williams J, Pisarska MD: Prevalence of chromosomal mosaicism in pregnancies from couples with infertility. Fertil. Steril., , 2008
  2. Kawamura K, Sudo S, Kumagai J, Pisarska M, Hsu SY, Bathgate R, Wade J, Hsueh AJ: Relaxin research in the postgenomic era. Ann. N. Y. Acad. Sci., 1041: 1-7, 2005
  3. Kawamura K, Kumagai J, Sudo S, Chun SY, Pisarska M, Morita H, Toppari J, Fu P, Wade JD, Bathgate RA, Hsueh AJ: Paracrine regulation of mammalian oocyte maturation and male germ cell survival. Proc. Natl. Acad. Sci. U.S.A., 101(19): 7323-8, 2004
  4. Lee K, Pisarska MD, Ko JJ, Kang Y, Yoon S, Ryou SM, Cha KY, Bae J: Transcriptional factor FOXL2 interacts with DP103 and induces apoptosis. Biochem. Biophys. Res. Commun., 336(3): 876-81, 2005
  5. Luo CW, Pisarska MD, Hsueh AJ: Identification of a stanniocalcin paralog, stanniocalcin-2, in fish and the paracrine actions of stanniocalcin-2 in the mammalian ovary. Endocrinology, 146(1): 469-76, 2004
  6. Pisarska MD, Bae J, Klein C, Hsueh AJ: Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene. Endocrinology, 145(7): 3424-33, 2004

Lab Information

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