Vincent Funari, PhD

Director, Genomics Core, Biomedical Sciences
Phone:(310) 423-2544

Academic Appointments

Assistant Professor, Pediatrics

Awards and Activities

Clinical Research Funds Award for Research (CREF), GCRC, Cedars Sinai2010
Dean's Award, BU College of Arts and Sciences2000
Office of Technology Development Award, BU Office of Technology Development2000
Teaching Fellow Award, BU College of Arts and Sciences1998
American Society for Human Genetics2005 - 2012

Research Focus

Our lab is focused on custom approaches or solutions to genomic questions. This includes developing new wet lab techniques or bioinformatic approaches to analyze genomic information. We specialize in bioinformatic analysis of NGS data for microbiome profiling, RNA expression profiling, and exome analysis. Our novel genomic approaches have lead to identification of mutations that cause disease, established candidate disease gene using expression profiling, identified candidate miRNAs involved in diabetes, and identified fungal and bacterial profiles associated with gut diseases.

Research Contributions

Leader in the development of new bioinformatic approaches for gene expression profiling and genetics.
Currently developing new bioinformatic and wetlab approaches to microbiome profiling applications

Selected Publications

  1. Rock MJ, Prenen J, Funari VA, Funari TL, Merriman B, Nelson SF, Lachman RS, Wilcox WR, Reyno S, Quadrelli R, Vaglio A, Owsianik G, Janssens A, Voets T, Ikegawa S, Nagai T, Rimoin DL, Nilius B, Cohn DH: Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia. Nat. Genet., 40(8): 999-1003, 2008
  2. Lee H, O'Connor BD, Merriman B, Funari VA, Homer N, Chen Z, Cohn DH, Nelson SF: Improving the efficiency of genomic loci capture using oligonucleotide arrays for high throughput resequencing. BMC Genomics, 10: 646, 2009
  3. Day A, Dong J, Funari VA, Harry B, Strom SP, Cohn DH, Nelson SF: Disease gene characterization through large-scale co-expression analysis. PLoS ONE, 4(12): e8491, 2009
  4. Funari VA, Krakow D, Nevarez L, Chen Z, Funari TL, Vatanavicharn N, Wilcox WR, Rimoin DL, Nelson SF, Cohn DH: BMPER mutation in diaphanospondylodysostosis identified by ancestral autozygosity mapping and targeted high-throughput sequencing. Am. J. Hum. Genet., 87(4): 532-7, 2010
  5. Funari VA, Voevodski K, Leyfer D, Yerkes L, Cramer D, Tolan DR: Quantitative gene expression profiles in real time from expressed sequence tag databases. Gene Expr., 14(6): 321-36, 2010
  6. Funari VA, Day A, Krakow D, Cohn ZA, Chen Z, Nelson SF, Cohn DH: Cartilage-selective genes identified in genome-scale analysis of non-cartilage and cartilage gene expression. BMC Genomics, 8: 165, 2007

Lab Information

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