Services and Prices

Contact the RMI iPSC Core for a quote on any of these services.

Please select a service for more information:

Custom iPSC Generation

PSC Quality Control and Characterization Services

Biobanking and PSC Thawing

Imaging Services

Cell Lines

Custom MEF Generation


Custom iPSC Generation Packages

Includes generation of clonal iPSC lines for a patient sample provided by customer and Complete or Essential pluripotency characterization package. Please contact us for prices and IRB clearance if an iPSC line needs to be derived from fresh skin biopsy.

Source Package Characterization Suite Price
Fibroblasts 3 clones Complete $12,000
2 clones Complete $10,000
1 clone Complete $8,000
3 clones Essential $6,250
2 clones Essential $5,250
1 clone Essential $4,250
LCLs or peripheral blood 3 clones Complete $12,500
2 clones Complete $10,500
1 clone Complete $8,500
3 clones Essential $6,750
2 clones Essential $5,750
1 clone Essential $4,750

Complete Characterization Package includes: Mycoplasma Testing, AP Staining, ICC for Pluirpotency Markers, G-Band Karyotype, RT-qPCR for Endogenous Pluripotency gene expression, hPSC Scorecard Assay, EBNA1 gDNA PCR, Cell Line Authentication (STR)
Essential Characterization Package includes: Mycoplamsa Testing, AP Staining, ICC for Pluripotent Markers, G-Band Karyotype 

Source tissues can include: fibroblast (skin), fresh whole blood (PBMCs), MSCs, adipose cells, various stromal epithelial cell types, and lymphoblastoid cells lines (LCLs or EBV B-cells). The fresh blood must be collected in CPT tubes and centrifuged according to manufacturer's directions. All reprogramming is preformed using non-integrating techniques in defined media (serum and KSR-free) and feeder-free conditions (no MEFs). Cost for each patient line includes the expansion and banking of three thoroughly characterized clonal lines under feeder-free conditions. Each cell line will be accompanied by a rigorous Certificate of Analysis to ensure pluripotency, normal karyotype, embryoid body formation and a variety of services related to the characterization of the pluripotent state (see below).


Pluripotent Stem Cell (PSC) Quality Control and Characterization Services

The RMI iPSC Core offers a variety of assays to ensure the quality and pluripotency of PSC lines. PSC characterization is included in the custom iPSC generation service, or separately as needed. Please contact the iPSC Core for more information on any of our individual characterization services.

Service Requirements Price/ iPSC Line (1 clone) Price/ iPSC Line (3 clones)
Mycoplasma Testing Please provide the core with at least 1ml of 2-day-old conditioned media. The core regularly performs mycoplasma testing once a month. Contact the core for the next available mycoplasma testing date. $17 $50
Alkaline Phosphatase (AP) Staining Please provide the core with 1 well of 50-60% confluent cells. $40 $110
Immunocytochemistry (ICC) staining
SSEA4 + OCT4  
TRA-1-60 + NANOG
TRA-1-81 + SOX2
Please proved the core with 1 well of good quality cells that are at least 50-60% confluent. $80 $225
OCT 3/4 + NANOG (or SSEA4) Imaging/Flow Cytometry 6 samples, minimum, are required for running this assay. Price may be split between multiple investigators and Core can help coordinate. Please provide the core with 1 confluent well of each sample. $120 $330
G-Band Karyotype Please provide the core with 2 80% confluent wells. $450 $1,250
PluriTest Assay — Currently Unavailable Please provide the core with 1-2 80% confluent wells. $320 $900
RT-qPCR for endogenous/exogenous
pluripotency gene expression
Please provide the core with 1-2 wells of good quality cells that are at least 80% confluent. $100 $280
Embryoid Body (EB) formation,
RT-PCR gene expression for 3 lineages
Please provide the core with a 70-80% confluent 6-well plate of cells. $340 $950
hPSC Scorecard Assay Price is per clone. Please provide the core with a 70-80% confluent 6-well plate of cells. We will generate EBs and also test parent iPSCs. This assay is done in pair of iPSCs + EBs generated from the iPSCs for 10-18 days. Price reflected is for the pair. $600 $1,500
EBNA1 gDNA PCR Confirm lack of exogenous plasmid presence. Price is per clone. $200 $550
Southern Blot Analysis Confirm lack of plasmid integration. $300 $850
Teratoma formation Price per clone. Contact the core for more information regarding teratoma formation. $2,500 $6,500


Biobanking and PSC Thawing

As part of the custom iPSC generation service, the core will expand and bank three fully characterized iPSC clones per cell line. This service is also available to iPSC and ESC lines generated outside of Cedars-Sinai.

Service Service Description Requirements Price
Cell Line Cryopreservation Guaranteed cryopreservation of high quality, mycoplasma negative cells (6 vials total-feeder free). Please provide the core with 1 well of starter cells. $150
PSC Thaw The core will thaw 1 vial of PSCs into 1 Matrigel coated well of a 6-well plate and maintain cells for 1 week. Please provide the core with 1 vial of cryopreserved cells. $50
PSC Thaw and Expansion The core will thaw 1 vial of PSCs into 1 Matrigel coated well of a 6-well plate and expand cells into a full 6-well plate over the course of 2 weeks.   Please provide the core with 1 vial of cryopreserved cells. $150
PSC Research Grade Biobank The core will generate a research grade bank of multiple cryopreserved vials of PSCs. Karyotype will be performed prior to initiating banking and at the time of creating a research grade lot. Contact Us


Imaging Services — Image Express Micro, Molecular Devices

Service Service Description Requirements Price
Image Express Micro Independent acquisition and analysis. User must be trained. $75/hr
Image Express Micro Staff assisted acquisition and analysis. User must be trained. $120/hr


Cell Lines

To see a complete list of available cell lines, please visit our Stem Cell Lines page. Prices listed reflect academic pricing only. Please contact the iPSC Core for information on industry pricing.


PSC Pricing

Item Volume Type Price*
hiPSCs or hESCs Cryovial Frozen $650
hiPSCs or hESCs 6-well plate Live Culture $120 ($20/well) + $650 (cost of vial) = $770
Reporter cell lines (iPSCs or ESCs) Nuclear GFP in AAVS1 safe harbor locus 6-well plate Live Culture $120
Reporter cell lines (iPSCs or ESCs) Nuclear GFP in AAVS1 safe harbor locus Cryovial Frozen $700

*Shipping will carry an additional cost


Custom Mouse Embryonic Fibroblast (MEF) Generation

Contact the core for custom generation of P1 and P2 non-mitomycin treated MEFs.