See a complete PubMed list of publications by Vaithi Arumugaswami, PhD.

Selected Key Publications

Ignatius Irudayam J, Contreras D, Spurka L, Subramanian A, Allen J, Ren S, Kanagavel V, Nguyen Q, Ramaiah A, Ramamoorthy K, French SW, Klein AS, Funari V, Arumugaswami V. Characterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection. Stem Cell Res. 2015;15(2):354-364.

Hatada S, Subramanian A, Mandefro B, Ren S, Kim HW, Tang J, Funari V, Baloh RH, Sareen D, Arumugaswami V, Svendsen CN. Low-dose irradiation enhances gene targeting in human pluripotent stem cells. Stem Cells Transl Med. 2015;4(9):998-1010.

Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 Jan 15;475:46-55.

Ren S, Ignatius Irudayam J, Contreras D, Sareen D, Talavera-Adame D, Svendsen CN and Arumugaswami V. Bioartificial liver device based on induced pluripotent stem cell-derived hepatocytes. J Stem Cell Res Ther. 2015; 5:263. Doi:10.4172/2157-7633.1000263.

Remenyi R, Qi H, Su SY, Chen Z, Wu NC, Arumugaswami V, Truong S, Chu V, Stokelman T, Lo HH, Olson CA, Wu TT, Chen SH, Lin CY, Sun R. A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins. MBio. 2014;5(5):e01469-14.

Kurtovic S, Ng TT, Gupta A, Arumugaswami V, Chaiboonma KL, Aminzadeh MA, Makkar R, Dafoe DC, Talavera-Adame D. Leptin enhances endothelial cell differentiation and angiogenesis in murine embryonic stem cells. Microvasc Res. 2015 Jan;97:65-74.

Ren S, Contreras D, Arumugaswami V. A protocol for analyzing hepatitis C virus replication. J Vis Exp. 2014 Jun 26;(88):e51362.

Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle.
Virology. 2014 Apr;454-455:118-127.

Dolan PT, Zhang C, Khadka S, Arumugaswami V, Vangeloff AD, Heaton NS, Sahasrabudhe S, Randall G, Sun R, LaCount DJ. Identification and comparative analysis of hepatitis C virus-host cell protein interactions. Mol Biosyst. 2013;9(12):3199-3209.!divAbstract.

Lassmann B, Arumugaswami V, Chew KW, Lewis MJ. A new system to measure and compare hepatitis C virus replication capacity using full-length, replication competent viruses. J Virol Methods. 2013;194(1-2):82-88.

Talavera-Adame D, Gupta A, Kurtovic S, Chaiboonma KL, Arumugaswami V, Dafoe DC. Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev. 2013;22(24):3252-3260.

Suhane S, Kanzaki H, Arumugaswami V, Murali R, Ramanujan VK. Mitochondrial NDUFS3 expression regulates the ROS-mediated onset of aerobic glycolysis in transformed cells. Biol Open. 2013;2(3):295-305.

Khachatoorian R, Arumugaswami V, Ruchala P, Raychaudhuri S, Maloney EM, Miao E, Dasgupta A, French SW. A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A mediated translation and virus production. Hepatology. 2012;55(6):1662-1672.

Noh C, Cho H, Kang H, Jin H, Lee S, Deng H, Wu TT, Arumugaswami V, Sun R, Song MJ. The virion-associated ORF49 of murine gammaherpesvirus 68 promotes viral replication both in vitro and in vivo. J Virol. 2012;86(2):1109-1118.

Gonzalez O, Fontanes V, Raychaudhuri S, Loo R, Loo J, Arumugaswami V, Sun R, Dasgupta A, French SW. Heat shock proteins inhibitors attenuate hepatitis C virus production. Hepatology. 2009;50(6):1756-1764.