Publications

See a complete PubMed list of publications by Kenneth Bernstein, MD.


Selected Key Publications

Shah KH, Shi P, Giani JF, Janjulia T, Bernstein E, Li Y, Zhao T, Harrison DG, Bernstein KE, Shen XZ. Myeloid suppressor cells accumulate and regulate blood pressure in hypertension. Circ Res. 2015 Aug 20. [epub ahead of print] http://circres.ahajournals.org/content/early/2015/08/20/CIRCRESAHA.115.306539.abstract.

Giani JF, Bernstein KE, Janjulia T, Han J, Toblli JE, Shen XZ, Rodriguez-Iturbe B, McDonough AA, Gonzalez-Villalobos RA. Salt sensitivity in response to renal injury requires renal angiotensin-converting enzyme. Hypertension. 2015;66(3):534-542. http://hyper.ahajournals.org/content/66/3/534.

Shen XZ, Li Y, Li L, Shah KH, Bernstein KE, Lyden P, Shi P. Microglia participate in neurogenic regulation of hypertension. Hypertension. 2015;66(2):309-316. http://hyper.ahajournals.org/content/66/2/309.

Garcia V, Joseph G, Shkolnik B, Ding Y, Zhang FF, Gotlinger K, Falck JR, Dakarapu R, Capdevila JH, Bernstein KE, et al. Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension. Am J Physiol Regul Integr Comp Physiol. 2015;309(1):R71-78. http://ajpregu.physiology.org/content/309/1/R71.

Giani JF, Shah KH, Khan Z, Bernstein EA, Shen XZ, McDonough AA, Gonzalez-Villalobos RA, Bernstein KE. The intrarenal generation of angiotensin II is required for experimental hypertension. Curr Opin Pharmacol. 2015 Apr;21:73-81. http://www.sciencedirect.com/science/article/pii/S147148921500003X.

Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, Amarnath K, Guzik TJ, Bernstein KE, et al. DC isoketal-modified proteins activate T cells and promote hypertension. J Clin Invest. 2014;124(10):4642-4656. http://www.jci.org/articles/view/74084.

Giani JF, Janjulia T, Taylor B, Bernstein EA, Shah K, Shen XZ, McDonough AA, Bernstein KE, Gonzalez-Villalobos RA. Renal generation of angiotensin II and the pathogenesis of hypertension. Curr Hypertens Rep. 2014;16(9):477. http://link.springer.com/article/10.1007%2Fs11906-014-0477-1.

Bernstein KE, Koronyo Y, Salumbides BC, Sheyn J, Pelissier L, Lopes DH, Shah KH, Bernstein EA, Fuchs DT, Yu JJ, et al. Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline. J Clin Invest. 2014;124(3):1000-1012. http://www.jci.org/articles/view/66541.

Gonzalez-Villalobos RA, Janjoulia T, Fletcher NK, Giani JF, Nguyen MT, Riquier-Brison AD, Seth DM, Fuchs S, Eladari D, Picard N, Bachmann S, Delpire E, Peti-Peterdi J, Navar LG, Bernstein KE, McDonough AA. The absence of intrarenal ACE protects against hypertension. J Clin Invest. 2013;123(5):2011-2023. http://www.jci.org/articles/view/65460.

Shen XZ, Billet S, Lin C, Okwan-Duodu D, Chen X, Bernstein KE. The carboxypeptidase angiotensin converting enzyme (ACE) shapes the MHC class I peptide repertoire. Nat Immunol. 2011;12(11):1078-1085. http://www.nature.com/ni/journal/v12/n11/full/ni.2107.html.

Fuchs S, Frenzel K, Hubert C, Lyng R, Muller L, Michaud A, Xiao HD, Adams JW, Capecchi MR, Corvol P, Shur BD, Bernstein KE. Male fertility is dependent on dipeptidase activity of testis ACE. Nat Med. 2005;11(11):1140-1142. http://www.nature.com/nm/journal/v11/n11/full/nm1105-1140.html.

Cole J, Ertoy D, Lin H, Sutliff RL, Ezan E, Guyene TT, Capecchi M, Corvol P, Bernstein KE. Lack of angiotensin II–facilitated erythropoiesis causes anemia in angiotensin-converting enzyme–deficient mice. J Clin Invest. 2000;106(11):1391-1398. http://www.jci.org/articles/view/10557.

Esther CR, Marino EM, Howard TE, Corvol P, Capecchi MR, Bernstein KE. The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. J Clin Invest. 1997;99(10):2375-2385. http://www.jci.org/articles/view/119419.

Marrero MB, Schieffer B, Paxton WG, Heerdt L, Berk BC, Delafontaine P, Bernstein KE. Direct stimulation of Jak/STAT pathway by the angiotensin II AT(1) receptor. Nature. 1995;375(6528):247-250. http://www.nature.com/nature/journal/v375/n6528/abs/375247a0.html.

Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE. Isolation of a cDNAencoding the vascular type-1 angiotensinII receptor. Nature. 1991;351(6323):233-236. http://www.nature.com/nature/journal/v351/n6323/abs/351233a0.html.

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