Publications

See a complete PubMed list of publications by Arkadiusz Gertych, PhD.

Selected Key Publications

Gertych A, Ing N, Ma Z, Fuchs TJ, Salman S, Mohanty S, Bhele S, Velásquez-Vacca A, Amin MB, Knudsen BS. Machine learning approaches to analyze histological images of tissues from radical prostatectomies. Comput Med Imaging and Graph. 2015 Dec;46 Pt 2:197-208. http://www.medicalimagingandgraphics.com/article/S0895-6111%2815%2900118-4/abstract.

Gertych A, Ma Z, Tajbakhsh J, Velásquez-Vacca A, Knudsen BS. Rapid 3-D delineation of cell nuclei for high-content screening platforms. Comput Biol Med. 2015 Apr 25;pii:S0010-4825(15)00143-2. http://www.computersinbiologyandmedicine.com/article/S0010-4825(15)00143-2/abstract.

Qin Y, Walts AE, Knudsen BS, Gertych A. Computerized delineation of nuclei in liquid-based pap smears stained with immunohistochemical biomarkers. Cytometry B Clin Cytom. 2015;88(2):110-119. http://onlinelibrary.wiley.com/doi/10.1002/cyto.b.21193/abstract.

Gertych A, Mohan S, Maclary S, Mohanty S, Wawrowsky K, Mirocha J, Balzer B, Knudsen BS. Effects of tissue decalcification on the quantification of breast cancer biomarkers by digital image analysis. Diagn Pathol. 2014;9(1):213. http://www.diagnosticpathology.org/content/9/1/213.

Oh JH, Gertych A, Tajbakhsh J. Nuclear DNA methylation and chromatin condensation phenotypes are distinct between normally proliferating/aging, rapidly growing/immortal, and senescent cells. Oncotarget. 2013;4(3):474-493. http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=942.

Gertych A, Oh JH, Wawrowsky KA, Weisenberger DJ, Tajbakhsh J. 3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models. BMC Pharmacol Toxicol. 2013 Feb 11;14:11. http://www.biomedcentral.com/2050-6511/14/11.

Gertych A, Joseph AO, Walts AE, Bose S. Automated detection of dual p16/Ki67 nuclear immunoreactivity in liquid-based Pap tests for improved cervical cancer risk stratification. Ann Biomed Eng. 2012;40(5):1192-1204. http://link.springer.com/article/10.1007%2Fs10439-011-0498-8.

Tajbakhsh J, Gertych A, Fagg WS, Hatada S, Fair JH. Early in vitro differentiation of mouse definitive endoderm is not correlated with progressive maturation of nuclear DNA methylation patterns. PLOS One. 2011;6(7):e21861. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021861.

Gertych A, Farkas DL, Tajbakhsh J. Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells. Exp Cell Res. 2010;316(19):3150-3160. http://www.sciencedirect.com/science/article/pii/S0014482710004076.

Gertych A, Wawrowsky KA, Vishnewsky E, Lindsley E, Farkas DL, Tajbakhsh J. Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment. Cytometry A. 2009;75(7):569-583. http://onlinelibrary.wiley.com/doi/10.1002/cyto.a.20740/abstract;jsessionid=844E7C95EC942D295EC989080406FD70.f02t04.