See a complete PubMed list of publications by Helen Goodridge, PhD.

Selected Key Publications

Yáñez A, Ng MY, Hassanzadeh-Kiabi N, Goodridge HS. IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production. Blood. 2015 Feb 26;125(9):1452-1459.

Khosravi A, Yáñez A, Price JG, Chow A, Merad M, Goodridge HS, Mazmanian SK. Gut microbiota promote hematopoiesis to control bacterial infection. Cell Host Microbe. 2014 Mar 12;15(3):374-381.

Goodridge HS. Editorial: Bone marrow progenitors share their experiences with their offspring. J Leuko Biol. 2014 Feb;95(2):201-204.

Goodridge HS. Induced pluripotent stem cell-derived myeloid phagocytes: disease modeling and therapeutic applications. Drug Discov Today. 2014 Jun;19(6):774-780.

Yáñez A, Goodridge HS, Gozalbo D, Gil ML. TLRs control hematopoiesis during infection. Eur J Immunol. 2013 Oct;43(10):2526-2533.

Yáñez A, Hassanzadeh-Kiabi N, Ng MY, Megías J, Subramanian A, Liu GY, Underhill DM, Gil ML, Goodridge HS. Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce. Eur J Immunol. 2013 Aug;43(8):2114-2125.  

Underhill DM, Goodridge HS. Information processing during phagocytosis. Nat Rev Immunol. 2012 Jun 15;12(7):492-502.

Goodridge HS, Underhill DM, Touret N. Mechanisms of Fc receptor and dectin-1 activation for phagocytosis. Traffic. 2012 Aug;13(8):1062-1071.

Goodridge HS, Reyes CN, Becker CA, et al. Activation of the innate immune receptor dectin-1 upon formation of a ‘phagocytic synapse'. Nature. 2011 Apr 28;472(7344):471-475.

Goodridge HS, Shimada T, Wolf AJ, et al. Differential use of CARD9 by dectin-1 in macrophages and dendritic cells. J Immunol. 2009 Jan 15;182(2):1146-1154.

Goodridge HS, Wolf AJ, Underhill DM. β-glucan recognition by the innate immune system. Immunol Rev. 2009 Jul;230(1):38-50.

Underhill DM, Goodridge HS. The many faces of ITAMs. Trends Immunol. 2007 Feb;28(2):66-73.

Goodridge HS, Simmons RM, Underhill DM. Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol. 2007 Mar 1;178(5):3107-3115.

Goodridge HS, Marshall FA, Else KJ, et al. Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62. J Immunol. 2005 Jan 1;174(1):284-293.

Goodridge HS, Marshall FA, Wilson EH, et al. In vivo exposure of murine dendritic cells and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype. Immunology. 2004 Dec;113(4):491-498.

Goodridge HS, Wilson EH, Harnett W, et al. Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae. J Immunol. 2001 Jul 15;167(2):940-945.