Click here for a complete list of Helen Goodridge, PhD publications.

Selected Key Publications

Yáñez A, Hassanzadeh-Kiabi N, Ng MY, Megías J, Subramanian A, Liu GY, Underhill DM, Gil ML, Goodridge HS. Detection of a TLR2 agonist by hematopoietic stem and progenitor cells (HPSCs) impacts the function of the macrophages they produce. European Journal of Immunology (2013, in press) DOI: 10.1002/eji.201343403

Underhill DM, Goodridge HS. Information processing during phagocytosis. Nature Reviews Immunology (2012) 12:492-502

Goodridge HS, Underhill DM, Touret N. Mechanisms of Fc receptor and Dectin-1 activation for phagocytosis. Traffic (2012) 13:1062-1071

Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan AS, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’. Nature (2011) 472:471-475

Goodridge HS, Shimada T, Wolf AJ, Hsu Y-MS, Becker CA, Lin X, Underhill DM. Differential utilization of CARD9 by Dectin-1 in macrophages and dendritic cells. Journal of Immunology (2009) 182:1146-1154

Goodridge HS, Wolf AJ and Underhill DM. b-glucan recognition by the innate immune system. Immunological Reviews (2009) 230:38-50

Underhill DM and Goodridge HS. The many faces of ITAMs. Trends in Immunology (2007) 28:66-73

Goodridge HS, Simmons RM and Underhill DM. Dectin-1 stimulation by Candida albicans yeast or zymosan triggers nuclear factor of activated T cells (NFAT) activation in macrophages and dendritic cells. Journal of Immunology (2007) 178:3107-3115

Goodridge HS, Marshall FA, Else KJ, Houston KM, Egan C, Al-Riyami L, Liew FY, Harnett W and Harnett MM. Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine (PC)-containing secreted product, ES-62. Journal of Immunology (2005) 174:284-293

Goodridge HS, Marshall FA, Wilson EH, Houston KM, Liew FY, Harnett MM and Harnett W. In vivo exposure of murine dendritic cells and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarises their differentiation to an anti-inflammatory phenotype. Immunology (2004) 113:491-498

Goodridge HS, Wilson EH, Harnett W, Campbell CC, Harnett MM and Liew FY. Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae. Journal of Immunology (2001) 167:940-945