Ramil earned her bachelor's degree at Wilkes University in Wilkes-Barre, Pennsylvania, where she participated in undergraduate research with William Terzaghi, PhD. She then worked in biopharmaceutical manufacturing at GlaxoSmithKline in Philadelphia before moving to San Diego on a whim. She joined the Gottlieb Laboratory in 2008 as a technician, maintaining the transgenic mouse colony and supporting the master's and PhD students, postdocs and scientists. Her current area of focus is refining the use of a novel mitochondria targeting protein, MitoTimer.
Allen M. Andres, PhD
Andres earned his PhD in molecular and cell biology in a joint doctoral program from San Diego State University and the University of California, San Diego, in 2009. He then joined the Gottlieb Laboratory as a postdoctoral fellow to investigate the role of mitochondrial turnover in cardioprotection. As a project scientist at Cedars-Sinai, his work now extends to studying the role mitophagy plays in the development of statin myopathy.
Jon Sin, PhD
Sin is studying the role of mitochondrial autophagy, or "mitophagy", during cellular differentiation. Stem cells undergo dramatic metabolic changes when they differentiate into mature adult cells. He is interested in the alterations that occur to the mitochondrial network and the interplay between mitophagy and mitochondrial biogenesis, which is crucial during the switch from glycolysis to oxidative phosphorylation. After graduating from University of California, San Diego, he completed his PhD at San Diego State University, where he was advised by Ralph Feuer, PhD, and Roberta Gottlieb, MD, on a project to determine the effect of coxsackievirus infection on cardiac progenitor cells.
David Taylor, PhD
Taylor is investigating the role glycogen autophagy may play in the heart. The autophagic removal of glycogen granules may benefit the ischemic heart by limiting the availability of glycolytic substrates, which can drive cellular acidosis and lead to worsened reperfusion injury. Furthermore, autophagic sequestration of glycogen may represent a novel point of metabolic control within the cell, with relevance for a number of pathological conditions. Taylor graduated in 2009 from the University of Hull in the UK, where he worked in the lab of Anne-Marie Seymour, PhD, investigating mitochondrial function in uremic cardiomyopathy.
Aleksandr Stotland, PhD
Stotland is currently using the MitoTimer protein to study mitophagy and mitobiogenesis in cardiac and muscle cells during stress, differentiation, and aging. He is also studying the mechanisms behind the protection of nuclear-encoded mitochondrial protein mRNAs on the mitochondria. Stotland received his bachelor's degree in biology from University of California, San Diego and completed his PhD in cell and molecular biology at San Diego State University, in the laboratory of Roland Wolkowicz, PhD, focusing on development of new tools for drug discovery in the field of HIV-1 and HCV.
Bruno B. Queliconi
Visiting Graduate Student
Queliconi did his undergraduate work in the Institute of Biosciences of the University of Sao Paulo, Sao Paulo, Brazil, and is currently working to complete his doctoral degree at the Institute of Chemistry, University of Sao Paulo. His thesis project examines the molecular basis of pH-independent redox injury associated with high bicarbonate. In addition to this project, he is interested in mitochondrial respiration and the impact of autophagy on mitochondrial efficiency and its role in redox control.
Martin joined the Gottlieb team in January 2014 after completing music industry and jazz studies at California State University. After college, Jordan worked at a sales and marketing company as a district manager in Palmdale and Woodland Hills for four years, and an office manager for a law firm in Westwood for one year before stepping into his position as Roberta Gottlieb, MD, assistant at Cedars-Sinai.