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The Pierson Laboratory is devoted to understanding the pathological mechanisms involved in pediatric neurogenetic disorders. Tyler Mark Pierson, MD, PhD has extensive experience in the phenotyping and diagnoses of rare neurogenetic disorders using modern genomic technologies. In addition to directing our laboratory, Pierson is also a co-director of the Pediatric Neurogenetics and Neuromuscular Clinic of Cedars-Sinai, where much of this clinical work is performed. Our laboratory's research goal is to extend these diagnostic elements by using patient-derived induced pluripotent stem cells (iPSCs) to understand the mechanisms associated with pediatric neurogenetic disorders and to explore stem cell-based therapies for the delivery of therapeutic proteins.