See a complete PubMed list of publications by Robin Shaw, MD, PhD.

Selected Key Publications

Basheer WA, Shaw RM. Connexin 43 and CaV1.2 ion channel trafficking in healthy and diseased myocardium. Circ Arrhythm Electrophysiol. 2016 Jun;9(6):e001357.

Shaw RM. Rethinking the conceptual toolkit of organ gifting. N Z Med J. 2015 Sep 25;128(1422):63-68.

Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, et al. Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol. 2015 Mar 15;593(6):1347-1360.;jsessionid=0FC8C0D992FDA266E336CA73BF4D8B3E.f03t02.

Xiao S, Shaw RM. Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention. Trends Cardiovasc Med. 2015 Jul;25(5):379-389.

Fu Y, Xiao S, Hong T, Shaw RM. Cytoskeleton regulation of ion channels. Circulation. 2015 Feb 24;131(8):689-691.

Shaw RM, Bell LJ. 'Because you can't live on love': living kidney donors' perspectives on compensation and payment for organ donation. Health Expect. 2015 Dec;18(6):3201-3212.

Shaw RM. Desmosomal hotspots, microtubule delivery, and cardiac arrhythmogenesis. Dev Cell. 2014 Oct 27;31(2):139-140.

Hong T, Yang H, Zhang S, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014 Jun;20(6):624-632.

Smyth JW, Zhang SS, Sanchez JM, Lamouille S, Vogan JM, Hesketh GG, Hong T, Tomaselli GF, Shaw RM. A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia. Traffic. 2014 June;15(6):684-699.;jsessionid=802CF4143BFCB258EDA84B2A11EB6341.f01t01.

Smyth JW, Shaw RM. Autoregulation of connexin43 gap junction formation by internally translated isoforms. Cell Rep. 2013 Nov 14;5(3):611-618.

Smyth JW, Vogan JM, Buch PJ, Zhang SS, Fong TS, Hong TT, Shaw RM. Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res. 2012 Mar 30;110(7):978-989.

Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, DeMarco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012 Jun;9(6):961-967.

Hong TT, Smyth JW, Chu K, Vogan J, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012 May;9(5):812-820.

Hong TT, Smyth JW, Gao D, Chu K, Vogan J, Fong TS, Jensen BC, Colecraft, H, Shaw RM. BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol. 2010 Feb 16;8(2):e1000312.

Smyth JW, Hong TT, Gao D, Vogan J, Jensen BC, Fong TS, Simpson PC, Stainier DY, Chi NC, Shaw RM. Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest. 2010 Jan;120(1):266-279.