Publications

Gantner B, Simmons R, Canavera S, Akira S, Underhill DM. Collaborative induction of inflammatory responses by Dectin-1 and Toll-like receptor 2. J Exp Med. 2003;197:1107-1117.

Underhill DM, Goodridge H. The many faces of ITAMs. Trends in Immunology. 2007;28:66-73.

Goodridge H, Simmons R, Underhill DM. Dectin-1 stimulation by Candida albicans yeast or zymosan triggers nuclear factor of activated T cells (NFAT) activation in macrophages and dendritic cells. J Immunol. 2007;178:3107-15.

Shimada T, Park B, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. Staphylococcus aureus evades the lysozyme-based digestion of peptidoglycan that links phagocytosis and macrophage IL-1 secretion. Cell Host and Microbe.2010;7:38-49.

Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan A, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature. 2011;472:471-475.

Wolf AJ, Arruda A, Reyes CN, Kaplan AT, Shimada T, Shimada K, Arditi M, Liu G, Underhill DM. Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria. J Immunol.2011;187:6002-6010.

Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M, Rotter JI, Wang HL, McGovern DPB, Brown GD, Underhill DM. Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science. 2012;336:1314-1317.

Underhill DM, Goodridge HS. Information processing during phagocytosis. Nat Rev Immunol. 2012;12:492-502.

Ma J, Becker C, Lowell CA, Underhill DM. Dectin-1 triggered recruitment of LC3 to phagosomes facilitates MHC Class II presentation of fungal-derived antigens. J Biol Chem. 2012;287:34149-56.

Kaplan A, Ma J, Kyme P, Wolf AJ, Becker CA, Tseng CW, Liu GY, Underhill DM. Failure to induce interferon-beta production during Staphylococcus aureus infection contributes to pathogenicity. J Immunol. 2012;189:4537.

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