The most common symptom of LKS is the loss of speech or the ability to understand speech. This change may happen slowly or it may be sudden. Symptoms of aphasia include:
- Difficulty understanding words that were once familiar
- Difficulty recognizing words that were once familiar
Behavioral problems may also develop including:
- Attention deficit hyperactivity disorder (ADHD)
- Angry outbursts
- Being withdrawn
Causes and Risk Factors
LKS is very rare. It is most common in children between the ages of 3 and 7 years old.
LKS affects twice as many boys as girls.
The cause of LKS is unknown. Treatment that suppresses the immune system has been helpful for some children. This may suggest the condition is related to an autoimmune disorder.
At least one known case of LKS has been associated with a mutated gene known as GRIN2A.