The main symptom experienced by patients with primary aldosteronism is moderate to severe high blood pressure, which is often resistant to drug treatments and accompanied by low potassium levels.
Other symptoms include:
- Muscle weakness
- Sporadic temporary paralysis
Causes and Risk Factors
Many cases of primary aldosteronism are caused by a benign tumor in an adrenal gland; some are caused by overactivity of both adrenal glands, a condition known as bilateral adrenal hyperplasia.
In rare cases, the condition may be caused by cancerous tumors in the outer layer of an adrenal gland, or by a genetic condition known as glucocorticoid-remediable aldosteronism.
The condition is most common in people between the ages of 30 and 50.