Anti-Vinculin Antibody Levels in Patients with Gastroparesis


  • Gastroparesis

Study Name

Serum Anti-Vinculin Antibody Titers in Gastroparesis Patients: A Prospective Study (IRB no. 34670)


This study focuses on patients who are undergoing treatment for gastroparesis. Gastroparesis, also called delayed gastric emptying, is a condition consisting of a partial paralysis of the stomach, resulting in food remaining in the stomach for an abnormally long time. Researchers will analyze serum in gastroparesis patients to determine whether there is a relationship between disease and presence of antibodies that bind to the human protein, vinculin. Antibodies are substances produced by the body to fight infection. Participants’ blood will be drawn during a regularly scheduled appointment; this sample will be analyzed for anti-vinculin antibody levels.

Financial Disclosure: Dr. Pimentel receives royalty income or may receive future royalty income based on a patent, copyright or other intellectual property directly related to this research.


Inclusion Criteria:

  • Patients with gastroparesis who are seen at the GI Motility Clinic

Exclusion Criteria:

  • Children
  • Pregnancy
  • Non-English speakers

Principal Investigator

Mark Pimentel, MD


Kathleen-Shari Chua

Tahli Singer-Englar
Phone: 310-423-3792