Association of Methane on Breath Testing and Constipation


  • Constipation and irritable bowel syndrome

Study Name

Association of Methane on Breath Testing and Constipation: An Examination Using Anorectal Manometry (IRB no. 32044)


This study focuses on individuals who have irritable bowel syndrome (IBS) or constipation and who are undergoing anorectal manometry. The purpose of the study is to determine whether alterations of bacteria in the small intestine that produce methane result in symptoms of constipation. Participants will perform a breath test and complete questionnaires, which will provide researchers with more information about IBS and help develop new therapeutic options to treat IBS with constipation.


Inclusion Criteria

  • Adults between the ages 18-75 years presenting to a gastrointestinal motility specialist for anorectal manometry

Exclusion Criteria

  • Children
  • Pregnancy
  • Non-English speakers

Principal Investigator

Mark Pimentel, MD


Tahli Singer-Englar
Phone: 310-423-3792

Kathleen Shari Chua