Pilot of AbStats/AEGIS System for Detecting Motility Abnormalities

Condition

  • Motility disorders


Study Name

Pilot Analysis of AbStats Belt and Acoustic Esophago-Gastro-Intestinal Surveillance (AEGIS) System for Detecting Motility Abnormalities
(IRB no. 32500)


Summary

The purpose of this study is to test the investigational use of a device called Acoustic Esophago-Gastro-Intestinal Surveillance (AEGIS). When compared to existing manometry, Smart Pill and lactulose breath testing, AEGIS may identify unique audible patterns characteristic of the features of gastroinestinal motility, gastric and small bowel contractions and emptying, and small intestinal bacterial overgrowth. Researchers will perform AEGIS audio monitoring concurrently in patients receiving a small bowel manometry, Smart Pill and lactulose hydrogen breath tests as part of their clinical care, and will analyze AEGIS data correlated with these standard clinical tests.

Participants will also wear another investigational device called the AbStats belt, which detects gut sounds during the clinical procedure and transmits audio data to the AEGIS device for analysis.


Eligibility

Key Inclusion Criteria:

  • Patients referred to the Cedars-Sinai Motility Program who are already scheduled to undergo small bowel manometry, Smart Pill, or lactulose hydrogen breath tests

Key Exclusion Criteria:

  • Body mass index incompatible with placement of the belt
  • Cognitive inability to follow direction
  • Abdominal wall condition that disallows topical coverage

Please see additional list of inclusion and exclusion criteria.


Principal Investigator

Mark Pimentel, MD


Contact

Kathleen-Shari Chua
Email: kathleenshari.chua@cshs.org

Tahli Singer-Englar
Phone: 310-423-3792
Email: tahli.singerenglar@cshs.org