Validation of Breath Test Prototype


  • Small intestinal bacterial overgrowth

Study Name

Validation of a Point-of-Care Breath Test Prototype Gas Chromatograph
(IRB no. 42911)


The purpose of this study is to evaluate an investigational method of breath testing. Researchers aim to determine whether analysis of an additional gas, hydrogen sulfide, will improve their ability to diagnose and treat patients with small intestinal bacterial overgrowth (SIBO). The study will compare breath gas testing that includes measurement of hydrogen sulfide to the standard testing, which measures only methane and hydrogen gas.

The study will be conducted in just one visit. Breath testing will be taken and read by the standard testing method, as well as by the new prototype analyzer.

Financial disclosure: Mark Pimentel, MD, and other researchers associated with this study have filed a patent, copyright or other intellectual property directly related to this research. At this time, there is no financial value associated with this filed patent; however, it is possible that the investigators could receive royalty income or may receive future royalty income should the patent be licensed in the future.


Inclusion Criteria:

  • Patients who undergo a breath test study with lactulose, glucose, lactose or fructose

Exclusion Criteria:

  • Children
  • Pregnancy

Principal Investigator

Mark Pimentel, MD


Kathleen-Shari Chua

Tahli Singer-Englar
Phone: 310-423-3792