Effects of Hookah Smoking on Blood Flow to the Heart, Muscle and Skin


  • Hypertension

Study Name:

Pilot Data on Acute Effects of Hookah (Waterpipe) Smoking on the Sympathetic Neural Control of the Human Cardiovascular System




Harmful substances inhaled during hookah smoking have been linked to various health problems. The purpose of this study is to gain information about the direct effect of hookah smoking on the heart and blood vessels. Specifically, researchers aim to understand how hookah smoking affects the blood flow in the skin, leg muscle and heart. Also, researchers will examine the effect of hookah smoking on the nerves that control the heart and blood vessels.

Key Inclusion Criteria:

  • 18 to 39 years old
  • Habitual hookah smoker defined as having smoked hookah at least 12 times in the  past 12 months
  • Have not smoked cigarettes within the past 12 months

Key Exclusion Criteria:

  • Exhaled carbon monoxide level greater than 10 ppm as evidence of current or recent cigarette (excluded if smoked cigarette within 12 months) or hookah smoking (excluded if smoked hookah within past 72 hours)
  • History of cardiopulmonary disease (including asthma or use of an inhaler)
  • Use of any prescription medication with exception of oral contraceptive pills

Please see complete list of inclusion and exclusion criteria.

Principal Investigator:

Ronald Victor, MD


Florian Rader, MD
O’Neil Mason, MD
Michael Nelson, MD

Study Coordinator and Contact:

Mohamad Rashid
Phone: 424-315-2501
Email: mohamad.rashid@cshs.org



IRB No.:


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