22518 Review and Survey of CT Followed by MR in the Emergency Room Disease: Various Summary: Our findings are that the majority of MRI results are in agreement with CT scan results. This study surveys physicians to learn why CT scans are followed up by MRI scans; we plan to show participating physicians the results of the survey to find out if they still would have ordered the MRI given the expectation of low yield for additional clinical information.
25081 Cerebral Perfusion Imaging to Measure Cerebral Blood Volume in Patients with Acute Stroke, Chronic Cerebro-Occlusive Diseases and Intra-Cranial Neoplasm Status: Active Disease: Acute Stroke Summary: This is a pilot study to collect data on images acquired from the use of cerebral (brain) blood volume (CBV) mapping using Siemens Syngo Dyna CT® C-arm CT from a specific type of detector called a bi-plane detector system in patients with acute stroke. Comparison will be made to conventional Code Brain CT images obtained in the Emergency Room.
23893 Arterial Spin Labeling MRI Perfusion in Evaluating Brain Tumors: An Investigator Initiated Pilot Project Status: Active Disease: Brain Tumor Summary: This research study is designed to compare arterial-spin-labeling enhanced magnetic resonance imaging (MRI) to conventional contrast-enhanced MRI.
11546 ACRIN 6678--FDG-PET/CT as a Predictive Marker of Tumor Response and Patient Outcome: Prospective Validation in Non-Small Cell Lung Cancer Principal Investigator: Alan Waxman, MD Status: Recruitment closed Disease: Non-small cell lung cancer Summary: The purpose of this research study is to determine if FDG-PET/CT scans can help doctors determine if chemotherapy is effectively controlling non-small cell lung cancer. This will also test the hypothesis that FDG-PET/CT may be an early predictor of disease progression or regression.
17796 18F-Fluoride PET/CT Versus 99m-Tc-MDP Scanning for Detecting Bone Metastases: A Randomized, Multi-Center Trial to Compare Two Bone Imaging Techniques Principal Investigator: Alan D. Waxman, MD Status: Recruitment closed Disease: cancer with bone metastasis Summary: The purpose of this research study is to compare the accuracy of sodium fluoride 18F-NaF (a skeletal imaging PET tracer) for PET combined CT (computer tomography) scanning to the standard of care 99mTc-MDP (technetium-99m methylene disphosphonate) bone scanning for detecting cancer that has spread to the bone.
25150 ACRIN 6690 A Prospective, Multicenter Comparison of Multiphase Contrast-Enhanced CT and Multiphase Contrast-Enhanced MRI for Diagnosis of Hepatocellular Carcinoma and Liver Transplant Allocation Status: Recruitment closed Disease: hepatocellular carcinoma (liver cancer) Summary: This is a multicenter clinical trial to compare multiphase contrast-enhanced CT and MRI to explant pathology liver workup to establish the respective performance characteristics of these imaging modalities to accurately detect, diagnose, and stage hepatocellular cancer in patients with chronic liver disease.
21872 KAST Study: The Kiva™ System as a Vertebral Augmentation Treatment – A Safety and Effectiveness Trial Principal Investigator: M. Marcel Maya, MD Status: Recruitment closed Disease: vertebral compression fracture Summary: This study is being done to evaluate the safety and effectiveness of the Kiva VCF Treatment system in comparison to balloon kyphoplasty for the treatment of vertebral compression fractures caused by osteoporosis of the back or spine. This study is intended to see if these two treatments are equally safe and effective at treating this condition.
20732 A Pilot, Phase II , Open Label, Non-Randomized, Multi-Center Study of [F-18] HX4 Positron Emission Tomography (PET) to Detect Hypoxia in Tumors Status: Recruitment closed Disease: various cancers Summary: This research study is designed to test the investigational use of [F-18]HX4 radiopharmaceutical, a new tracer used for PET Scan imaging in patients with cancer.
19769 A Phase II, Open Label, Non-Randomized, Multi-Center, Pilot, Efficacy Study of [F-18]RGD-K5 Positron Emission Tomography (PET) As a Tool to Monitor Response to an Anti-Angiogenic Drug Status: Recruitment closed Disease: cancer treated with chemotherapy and Avastin® Summary: The primary objective for this study is to investigate the use of [F-18]RGD-K5 PET/CT to predict effectiveness or early response to Avastin® plus chemotherapy treatment before completion of the full course of standard chemotherapy. Principal Investigator: Franklin G. Moser, MD
17253 Prospective, Single Arm, Open Label Post-Market Pilot Study to Evaluate the StabiliT Vertebral Augmentation System Treat Vertebral Compression Fractures Due to Osteoporosis Status: Recruitment closed Disease: vertebral compression fracture Summary: This is a post-market surveillance pilot study to evaluate the D-Fine StabiliT Vertebral Augmentation System® to deliver to the fracture site a special bone cement to treat vertebral compression fractures due to osteoporosis.
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