A Screening Protocol to Determine Potential Eligibility of Patients with Brain Tumors for IRB-Approved Vaccine Trials

Condition/Intervention:

  • Brain tumor
    • Screening

Study Name:

A Screening Protocol to Determine Potential Eligibility of Patients with Brain Tumors for IRB-Approved Vaccine Trials

Summary:

The purpose of this study is to collect brain tumor samples taken during a scheduled surgical procedure to determine possible eligibility and interest in participating in current IRB-approved vaccine trials. The tumor tissue will be removed during the surgery regardless of research participation. The processed tumor tissue would then be maintained in a separate registry and analyzed for eligibility in any of the IRB-approved vaccine trials.

Financial Disclosure: Ray Chu, MD, and Keith Black, MD, who are co-investigators on this study, have a financial relationship with Immunocellular Therapeutics, Ltd. (ICT), the company that is sponsoring one of the approved vaccine trials. Christopher Wheeler, MD, who is a co-investigator on this study, is the inventor and holder of a patent application that was licensed to ICT. In addition, Cedars-Sinai is a significant shareholder of ICT, which is the sponsor providing financial support to manufacture the vaccines used in the trial.

Inclusion Criteria:

  • Adults and children identified as having a probable brain tumor which is best treated by surgical resection
  • Informed consent for:
    • processing of brain tumor removed during surgery
    • storing brain tumor tissue for possible inclusion in vaccine trials

Exclusion Criteria:

  • Women who are pregnant

Principal Investigator:

Jeremy Rudnick, MD

Study Coordinator and Contact:

Cherry Sanchez, RN
Phone: 310-423-6839
Email: cherry.sanchez@cshs.org

Status:

Enrolling

IRB No.:

09225

Date Last Updated:

02/15