Can Diet and Exercise Modulate Progression-Free Survival in Ovarian/Fallopian Tube/Primary Peritoneal Cancer Patients?

Condition/Intervention

  • Ovarian, fallopian tube or primary peritoneal cancer

Study Name

GOG-0225 Can Diet and Physical Activity Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival?

Summary

The purpose of this study is to evaluate whether a change in diet and exercise in women with ovarian, fallopian tube or primary peritoneal cancer has an effect on the length of time patients are cancer-free following initial treatment. The study will also examine whether the changes in diet and exercise improve overall quality of life and the ability to be physically active.

Half of the participants will follow a diet and physical activity intervention and will receive focused lifestyle coaching. The other participants will continue their usual diet and physical activity and will not be asked to change what they are doing; these women will also receive general lifestyle coaching.

Key Inclusion Criteria

  • Women 18 years of age and older
  • Diagnosis of epithelial ovarian cancer, fallopian tube or primary peritoneal carcinoma, clinical stage II, III or IV at diagnosis
  • Must have completed all primary chemotherapy and consolidation therapy at least six weeks, and no more than six months and two weeks, prior to enrollment; must be in complete remission

Key Exclusion Criteria

  • Gynecologic Oncology Group performance status of 3 or 4.
  • May not have a history of other invasive malignancies within the last five years, with the exception of non-melanoma skin cancer or stage 1A endometrioid adenocarcinoma of the uterus
  • Patients diagnosed with chronic disease/illness precluding their participation

Please see detailed eligibility information.

Principal Investigator

Bobbie Rimel, MD

Co-Investigators Include

Ilana Cass, MD
Julie Dunhill, MD
Beth Karlan, MD
Andrew Li, MD
Ronald Leuchter, MD
Christine Walsh, MD

Study Coordinator and Contact

Meredith Axtell
Phone: 310-423-6595
Email: meredith.axtell@cshs.org

Status

Active

IRB No.

29696

Date Last Updated

01/16