HB3 Study (Healthy Babies Before Birth)


  • Maternal fetal health

Study Name

Mechanisms and Effects of Perinatal Maternal Affect on Pregnancy and Infant Development


The purpose of this study is to understand how stress in pregnancy affects pregnancy outcomes, as well as the eventual health and development of the baby. Specifically, researchers will assess the effects of the mother’s mood on her immune system and stress level, in addition to its impact on the infant's behavior and immune system development. Researchers will also examine the cells involved in fighting infections to improve their understanding of cellular aging in women over the course of pregnancy and post-partum.

Key Inclusion Criteria

  • Pregnant women between eight and 16 weeks gestation
  • Between 18 and 45 years old
  • Willing and able to participate and sign informed consent

Key Exclusion Criteria

  • Evidence of current substance abuse
  • Currently smoking
  • HIV-positive status
  • Patients with immunologic or endocrinologic disease

Please see complete list of inclusion and exclusion criteria.

Principal Investigator

Calvin Hobel, MD


Tania Esakoff, MD
Susan Jackman, RN, MS

Study Coordinator and Contact

Susan Jackman, RN, MS
Phone: 310-423-4765
Email: susan.jackman@cshs.org





Date Last Updated