Short-Term Impact of Surgical Menopause on Cognitive Function in Women at Elevated Risk for Ovarian Cancer

Condition/Intervention

  • Surgical menopause

Study Name

Short-term Impact of Surgical Menopause on Cognitive Function in Women at Elevated Risk for Ovarian Cancer

Summary

The purpose of this study is to identify changes in memory and cognition that may result from surgical menopause in women at high risk of ovarian cancer who choose to reduce their risk of cancer by having their tubes and ovaries removed. The study will examine whether hormone replacement therapy has an effect on memory and cognition.

Researchers will collect information about personal and family history of cancer, along with personal demographics, lifestyle habits and medical history. A cognitive assessment tool will be utilized to better understand individuals at high risk for ovarian cancer.

Key Inclusion Criteria

  • Planning to have surgery to remove both ovaries or remaining ovary if only one ovary is intact
  • No personal history of ovarian, peritoneal, or tubal cancer
  • Menstrual cycles in the past six months or is not yet menopausal
  • Currently has at least one ovary intact

Key Exclusion Criteria

  • Pregnant women
  • Children

Please see complete list of inclusion and exclusion criteria.

Principal Investigator

Ilana Cass, MD

Co-Investigators Include

Daniella Kamara, MS, LCGC
Beth Y. Karlan, MD
Andrew Li, MD
Ronald Leuchter, MD
Bobbie Rimel, MD
Christine Walsh, MD

Study Coordinator and Contact

Daniella Kamara, MS, LCGC
Phone: 310-423-9966
daniella.kamara@cshs.org

Status

Active

IRB No.

36538

Date Last Updated

01/16