Previous Research: Examining the Role of Insulin Clearance During Insulin Resistance

Kim SP. Mechanisms underlying restoration of hepatic insulin sensitivity with CB1 antagonism in the obese dog model. Adipocyte. 2013 Jan 1;2(1):47-49.

Kim SP, Woolcott OO, Hsu IR, Stefanovski D, Harrison LN, Zheng D, Lottati M, Kolka C, Catalano KJ, Chiu JD, et al. CB(1) antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs. Am J Physiol Endocrinol Metab. 2012 May 1;302(10):E1261-1268.

Kim SP, Ellmerer M, Van Citters GW, Bergman RN. Primacy of hepatic insulin resistance in the development of the metabolic syndrome induced by an isocaloric moderate-fat diet in the dog. Diabetes. 2003 Oct;52(10):2453-2460.

Kim SP, Ellmerer M, Kirkman EL, Bergman RN. Beta-cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model. Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1581-1589.

Kim SP, Catalano KJ, Hsu IR, Chiu JD, Richey JM, Bergman RN. Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1590-1598.

Bergman RN, Stefanovski D, Kim SP. Systems analysis and the prediction and prevention of Type 2 diabetes mellitus. Curr Opin Biotechnol. 2014 Aug;28C:165-170.

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