Previous Research: Islet Beta Cell Research on Insulin Secretion

Woolcott OO, Richey JM, Kabir M, Chow RH, Iyer MS, Kirkman EL, Stefanovski D, Lottati M, Kim SP, Harrison LN, et al. High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. PLOS One. 2015;10(4):e0123558.

Woolcott OO, Bergman RN, Richey JM, Kirkman EL, Harrison, LN, Ionut V, Lottati M, Zheng D, Hsu IR, Stefanovski D, et al. Simplified method to isolate highly pure canine pancreatic islets. Pancreas. 2012 Jan;41(1):31-38.

Woolcott OO, Gustafsson AJ, Dzabic M, Pierroa C, Tedeschia P, Sandgrena J, Rizuanul Baria M, Hoab NK, Bianchia M, Rakonjacc M, et al. Arachidonic acid is a physiological activator of the ryanodine receptor in pancreatic beta cells. Cell Calcium. 2006 Jun;39(6):529-537.

Woolcott OO, Richey JM, Chow RH, Kabir M, Iyer M, Kirkman EL, Stefanovski D, Lottati M, Harrison IN, Ionut V, et al. Physiological anandamide levels potentiate glucose-stimulated insulin secretion in isolated canine pancreatic islets. 71st Scientific Sessions 2011;1840-P.

Woolcott OO, Richey JM, Stefanovski D, Ader M, Yae S, Dittman J, Chow RH, Kirkman E, Bergman, RN. Larger pancreatic islets compensate relatively more than smaller islets in response to diet-induced insulin resistance in dogs. 70th Scientific Sessions 2010: 1723-P.

Woolcott OO, Richey JM, Chow R, Kirkman EL, Stefanovski D, Hsu IR, Lottati M, Ionut V, Zheng D, Harrison LN, et al. Evidence of increased CB-1 receptor activity in isolated pancreatic islets from high fat-fed dogs. 69th Scientific Sessions 2009:1643-P.

Richey JM, Woolcott OO, Stefanovski D, Harrison LN, Zheng D, Lottati M, Hsu IR, Kim SP, Kabi M, Catalano KJ, et al. Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs. Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1311-8.

Richey JM, Woolcott OO, Kim SP, Stefanovski D, Ionut V, Catalano K, Chiu J, Hsu I, Harrison L, Lottati M, et al. Effect of CB-1 antagonist (rimonabant) to increase insulin sensitivity, independent of weight loss. 67th Scientific Sessions 2007: 0248-OR.

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