Lung Research Programs

Our investigators are exploring genetic mutations, pathogens and microbes that cause chronic bacterial infections as well as immune response and antibiotic resistance in the lungs of patients with cystic fibrosis, an inherited disease.

Research in the Women's Guild Lung Institute studies the molecular mechanisms of lung injury, repair and fibrosis to develop effective therapies for interstitial lung diseases, which cause scarring that is usually irreversible.

Our investigators are researching abnormal cell division and the mechanisms of tumor progression in small cell and non-small cell lung cancers to discover immunotherapies, including targeted drug therapies and other treatments.

Our research in pulmonary immunology focuses on the innate immunity of lung cells and the intricate innate immune system to reveal origination of infection and mechanisms that prevent as well as advance disease.

Our researchers are developing effective therapies by investigating the roles of innate immune components, immunoregulatory and molecular mechanisms, and microRNA in lung injury.

Lung transplant is a surgical option for cystic fibrosis, emphysema, pulmonary fibrosis and pulmonary hypertension. Our investigators are studying medications to minimize transplant rejection and improve outcomes and quality of life for transplant patients.

Our team is discovering better ways to support patients who have chronic and advanced lung disease to help them understand medical procedures, control symptoms and achieve a better quality of life.

We are examining the pathophysiology of pulmonary embolism to explore risk factors for thromboembolic events and develop novel treatments to prevent clotting, reduce risk of a blockage and resolve chronic blood clots.

Our researchers are using lung stem cells to identify critical determinants of lung epithelial maintenance, renewal and remodeling that can lead to more effective therapies for fibroproliferative lung diseases.