Publications

Minciacchi VR, You S, Spinelli C, Morley S, Zandian M, Aspuria PJ, Cavallini L, Ciardiello C, Reis Sobreiro M, Morello M, Kharmate G, Jang SC, Kim DK, Hosseini-Beheshti E, Tomlinson Guns E, Gleave M, Gho YS, Mathivanan S, Yang W, Freeman MR, Di Vizio D. Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles. Oncotarget. 2015 Mar 14. http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=3598. [Epub ahead of print.]

Minciacchi VR, Freeman MR, Di Vizio D. Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes. Semin Cell Dev Biol. 2015 Apr;40:41-51. http://www.sciencedirect.com/science/article/pii/S1084952115000373.

Kim OY, Choi SJ, Jang SC, Park KS, Kim SR, Choi JP, Lim JH, Lee SW, Park J, Di Vizio D, Lötvall J, Kim YK, Gho YS. Bacterial protoplast-derived nanovesicles as vaccine delivery system against bacterial infection. Nano Lett. 2015 Jan 14;15(1):266-274. http://pubs.acs.org/doi/abs/10.1021/nl503508h.

Jang SC, Kim SR, Yoon YJ, Park KS, Kim JH, Lee J, Kim OY, Choi EJ, Kim DK, Choi DS, Kim YK, Park J, Di Vizio D, Gho YS. In vivo kinetic biodistribution of nano-sized outer membrane vesicles derived from bacteria. Small. 2015 Jan 27;11(4):456-461. http://onlinelibrary.wiley.com/doi/10.1002/smll.201401803/abstract.

Lötvall J, Hill AF, Hochberg F, Buzás EI, Di Vizio D, Gardiner C, Gho YS, Kurochkin IV, Mathivanan S, Quesenberry P, et al. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. J Extracell Vesicles. 2014 Dec 22;3:26913. http://www.journalofextracellularvesicles.net/index.php/jev/article/view/26913.

D'Souza-Schorey C, Di Vizio D. Biology and proteomics of extracellular vesicles: harnessing their clinical potential. Expert Rev Proteomics. 2014 Jun;11(3):251-253. http://informahealthcare.com/doi/full/10.1586/14789450.2014.874290.

Morello M, Minciacchi VR, de Candia P, Yang J, Posadas E, Kim H, Griffiths D, Bhowmick N, Chung LW, Gandellini P, Freeman MR, Demichelis F, Di Vizio D. Large oncosomes mediate intercellular transfer of functional microRNA. Cell Cycle. 2013 Sep 23;12(22). https://www.landesbioscience.com/journals/cc/article/26539/.

Israelsen WJ, Dayton TL, Fiske BP, Hosios A, Bellinger G, Li J, Yu J, Sasaki M, Horner JW, Burga LN, Xie J, DePinho RA, Jacks T, Wulf GM, Di Vizio D, et al. PKM2 deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell. 2013;155(2):397-409. http://www.sciencedirect.com/science/article/pii/S0092867413011628.

Ayala G, Morello M, Frolov A, You S, Li R, Rosati F, Bartolucci G, Danza G, Adam RM, Thompson TC, Lisanti MP, Freeman MR, Di Vizio D. Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumor progression. J Pathol. 2013 Sep;231(1):77-87. http://onlinelibrary.wiley.com/doi/10.1002/path.4217/abstract.

Di Vizio D, Morello M, Dudley AC, Schow PW, Adam RM, Morley S, Mulholland D, Rotinen M, Hager MH, Insabato L, et al. Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am J Pathol. 2012;181(5):1573-1584. http://ajp.amjpathol.org/article/S0002-9440(12)00600-1/fulltext.

Hager MH, Morley S, Bielenberg DR, Gao S, Matteo M, Holcomb IN, Liu W, Mouneimne G, Demichelis F, Kim J, Solomon KR, Adam RM, Isaacs WB, Higgs HN, Vessella RL, Di Vizio D, Freeman MR. DIAPH3 governs the cellular transition to the amoeboid tumor phenotype. EMBO Mol Med. 2012;4:743-760. http://embomolmed.embopress.org/content/4/8/743.

Freeman MR, Yang W, Di Vizio D. Caveolin-1 and prostate cancer progression. Adv Exp Med Biol. 2012;729:95-110. http://rd.springer.com/chapter/10.1007%2F978-1-4614-1222-9_7.

Freeman MR, Kim J, Lisanti MP, Di Vizio D. A metabolic perturbation by UO126 identifies a role for glutamine in resveratrol-induced cell death. Cancer Biol Ther. 2011 Dec 1;12(11):966-77. https://www.landesbioscience.com/journals/cbt/article/18136/.

Di Vizio D, Morello M, Sotgia F, Pestell RG, Freeman MR, Lisanti MP. An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt-activation. Cell Cycle. 2009 Aug;8(15):2420-2424. https://www.landesbioscience.com/journals/cc/article/9116/.

Di Vizio D, Kim J, Hager MH, Morello M, Yang W, Lafargue CJ, True LD, Rubin MA, Adam RM, Beroukhim R, et al. Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res. 2009 Jul 1;69(13):5601-5609. http://cancerres.aacrjournals.org/content/69/13/5601.