Personal Statement

The goal of the Gonzalez Laboratory is to evaluate the role of angiogenic factors in the development of stroke and transient ischemic attack in patients with internal carotid artery stenosis (ICAS). We also focus on the effects of encephaloduroarteriosynangiosis (EDAS) revascularization in the local cerebral microenvironment and the potential role of circulating angiogenic cells in this process.

As a physician and scientist, I have dedicated my career to the study and treatment of cerebrovascular disorders through a demanding and unique training, with completed residencies in radiology and neurosurgery, and additional research training, earning a master of science in clinical and translational research.

The National Institutes of Health, the American Heart Association and philanthropic support, including the Oppenheimer Award and the Ruth and Raymond Stotter Endowment, have recognized my commitment and aptitude for research. This work has resulted in numerous published peer-reviewed papers in the treatment of cerebrovascular problems and specifically on subjects relevant to our laboratory work.

Initial research from the Gonzalez Laboratory received two Innovation Science Research Awards from the American Heart Association that allowed us to complete the preliminary work used in support of the feasibility and promise of our current projects. Beyond those investigations in angiogenesis and circulating angiogenic cells, I conducted studies that have led to the use of EDAS revascularization as an alternative treatment for adult patients with cerebral arterial steno-occlusive disorders, including moyamoya and ICAS.

I am optimistic that research in the Gonzalez Lab can open novel avenues for the management of devastating forms of stroke for which there are currently no definitive, successful treatments.