See a complete PubMed list of publications by Mark Goodarzi, MD, PhD.

Selected Key Publications

Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L,…Goodarzi MO, et al. Low-frequency and rare exome chip variants associate with fasting glucose and Type 2 diabetes susceptibility. Nat Commun. 2015 Jan 29;6:5897.

Palmer ND, Goodarzi MO, Langefeld CD, Wang N, Guo X, Taylor KD, Fingerlin TE, Norris JM, Buchanan TA, Xiang AH, et al. Genetic variants associated with quantitative glucose homeostasis traits translate to Type 2 diabetes in Mexican Americans: the GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes 2015;64(5):1853-1866.

Goodarzi MO, Li X, Krauss RM, Rotter JI, Chen YDI. Relationship of sex to diabetes risk in statin trials. Diabetes Care 2013;36(7):e100-101.

Goodarzi MO, Guo X, Cui J, Jones MR, Haritunians T, Xiang AH, Chen YDI, Taylor KD, Buchanan TA, Hsueh WA, et al. Systematic evaluation of validated Type 2 diabetes and glycemic trait loci for association with insulin clearance. Diabetologia 2013;56(6):1282-1290.

Lee CC, Haffner SM, Wagenknecht LE, Lorenzo C, Norris JM, Bergman RN, Stefanovski, Anderson AM, Rotter JI, Goodarzi MO*, Hanley AJG*. Insulin clearance and the incidence of Type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. Diabetes Care 2013;36(4):901-907. *Equal senior author status.

Jones MR, Chazenbalk G, Xu N, Chua A, Eigler T, Mengesha E, Chen Y-H, Lee J-M, Pall M, Li X, Chen YDI, Taylor KD, Mathur R, Krauss RM, Rotter JI, Legro RS, Azziz R, Goodarzi MO. Steroidogenic regulatory factor FOS is underexpressed in polycystic ovary syndrome (PCOS) adipose tissue and genetically associated with PCOS susceptibility. J Clin Endocrinol Metab. 2012;97(9):E1750-1757.

Guo X, Cui J, Jones MR, Haritunians T, Xiang AH, Chen YD, Taylor KD, Buchanan TA, Davis RC, Hsueh WA, Raffel LJ, Rotter JI, Goodarzi MO. Insulin clearance: confirmation as a highly heritable trait, and genome-wide linkage analysis. Diabetologia 2012;55(8):2183-2192.

Goodarzi MO, Jones MR, Li X, Chua A, Garcia O, Chen YDI, Krauss RM, Rotter JI, Ankener W, Legro RS, et al. Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts. J Med Genet. 2012;49(2):90-95.

Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim J-H, Goode J, Igata M, Paz J, et al. CRTC3 links catecholamine signaling to energy balance. Nature 2010;468(7326):933-939.

Rich SS*, Goodarzi MO*, Palmer ND, Langefeld CD, Ziegler J, Haffner SM, Bryer-Ash M, Norris JM, Taylor KD, Haritunians T, et al. A genome-wide association scan for acute insulin response to glucose in Hispanic Americans: the IRAS Family Study. Diabetologia 2009;52(7):1326-1333. *Equal first author status.

Goodarzi MO, Jones MR, Chen YDI, Azziz R. AKT2: First evidence of genetic association between AKT2 polycystic ovary syndrome. Diabetes Care 2008;31(12):2284-2287.

Goodarzi MO, Lehman DM, Taylor KD, Guo X, Cui J, Quiñones MJ, Clee SM, Yandell BS, Blangero J, Hsueh WA, et al. SORCS1: a novel human Type 2 diabetes susceptibility gene suggested by the mouse. Diabetes 2007;56(7):1922-1929.

Goodarzi MO, Taylor KD, Guo X, Quiñones MJ, Cui J, Saad MF, Yang H, Hsueh WA, Hodis HN, Rotter JI.  Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study. Diabetes 2005;54(4):1228-1232.

Goodarzi MO, Taylor KD, Guo X, Quiñones MJ, Cui J, Li X, Hang T, Yang H, Holmes E, Hsueh WA, et al.  Variation in the gene for muscle-specific adenosine monophosphate deaminase is associated with insulin clearance, a highly heritable trait. Diabetes 2005;54(4):1222-1227.

Goodarzi MO, Guo X, Taylor KD, Quiñones MJ, Saad MF, Yang H, Hsueh WA, Rotter JI.  Lipoprotein lipase is a gene for insulin resistance in Mexican-Americans. Diabetes 2004;53(1):214-220.