Myeloid Cell Differentiation and Function
Hematopoietic stem cells (HSCs) give rise to all the different types of blood cells, including myeloid phagocytes (neutrophils, monocytes, macrophages and dendritic cells). Myeloid phagocytes are immune cells that defend the body against invading microbes, and also play important roles in inflammatory diseases, aging and cancer. The Goodridge Laboratory is studying the development (a process known as myelopoiesis) and function of myeloid phagocytes.
The Goodridge Laboratory is affiliated with the Cedars-Sinai Board of Governors Regenerative Medicine Institute, Department of Biomedical Sciences, Immunology & Infectious Diseases Research, Department of Medicine, F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute and Cancer Institute. The lab has received funding from the National Institutes of Health, American Heart Association, American Association of Immunologists, American Society of Hematology, and Cedars-Sinai (Board of Governors Regenerative Medicine Institute and Cancer Institute).