Publications

See a complete PubMed list of publications by TingTing Hong, MD, PhD.

Selected Key Publications

Xie Y, Hitzeman TC, Zadikany RH, Nikolova AP, Baum R, Xu B, Agvanian S, Melmed GY, McGovern DT, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong TT, Shaw RM. Plasma cBIN1 score (CS) identifies HFrEF and can predict cardiac hospitalization in stable ambulatory patients. Preprints. Online January 7, 2018. https://www.preprints.org/manuscript/201801.0040/v1.

Nikolova AP, Hitzeman TC, Baum R, Xu B, Agvanian S, Xie Y, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong TT, Shaw RM. Plasma cBIN1 score (CS) identifies HFpEF and can predict cardiac hospitalization in stable ambulatory patients. Preprints. Online January 7, 2018. https://www.preprints.org/manuscript/201801.0041/v1.

Xu B, Fu Y, Liu Y, Agvanian S, Wirka RC, Baum R, Zhou K, Shaw RM, Hong T. The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles. PLoS Biol. 2017 Aug 14; 15(8):e2002354. http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2002354.

Hong T, Shaw RM. Cardiac T-tubule microanatomy and function. Physiol Rev. 2017 Jan; 97:227-252. http://www.physiology.org/doi/full/10.1152/physrev.00037.2015.

Fu Y, Shaw SA, Naami R, Vuong CL, Basheer WA, Guo X, Hong T. Isoproterenol promotes rapid ryanodine receptor movement to bridging integrator 1 (BIN1) – organized dyads. Circulation. 2016;133(4):388-397. http://circ.ahajournals.org/content/133/4/388.long.

Fu Y, Hong T. BIN1 regulates dynamic t-tubule membrane. Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1839-1847. http://www.sciencedirect.com/science/article/pii/S0167488915003808.

Fu Y, Xiao S, Hong T, Shaw RM. Cytoskeleton regulation of ion channels. Circulation. 2015;131(8):689-691. http://circ.ahajournals.org/content/131/8/689.

Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, et al. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014;20(6):624-632. http://www.nature.com/nm/journal/v20/n6/full/nm.3543.html.

Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, et al. BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012 May;9(5):812-820. http://www.heartrhythmjournal.com/article/S1547-5271(11)01455-X/abstract.

Smyth JW, Vogan JM, Buch PJ, Zhang SS, Fong TS, Hong T, Shaw RM. Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res. 2012;110(7):978-989. http://circres.ahajournals.org/content/110/7/978.

Hong T, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, et al. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012;9(6):961-967. http://www.heartrhythmjournal.com/article/S1547-5271(12)00083-5/abstract.

Hong T, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, et al. BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012;9(5):810-820. http://www.heartrhythmjournal.com/article/S1547-5271(11)01455-X/abstract.

Hong T, Smyth JW, Gao D, Chu KY, Vogan JM, Fong TS, Jensen BC, Colecraft HM, Shaw RM. BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLOS Biol. 2010;8(2):e1000312. http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1000312.

Smyth JW, Hong TT, Gao D, Vogan JM, Jensen BC, Fong TS, Simpson PC, Stainier DY, Chi NC, Shaw RM. Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest. 2010;120(1):266-279. http://www.jci.org/articles/view/39740.