See a complete PubMed list of publications by Jonathan Kaye, PhD.

Selected Key Publications

Page N, Klimek B, De Roo M, Steinbach K, Soldati H, Lemeille A Wagner I, Kreutzfeldt M, Di Liberto G, Vincenti I, Linger T, Salinas G, Brück W, Simons M, Murr R, Kaye J, et al. Expression of the DNA-binding factor TOX promotes the encephalitogenic potential of microbe-induced autoreactive CD8+ T cells. Immunity. 2018 May 15;48(5):937-950.

Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018 Jan 2;215(1):249-262.

Seehus CR, Kadavallore A, Torre B, Yeckes AR, Wang Y, Tang J, Kaye J. Alternative activation generates IL-10 producing type 2 innate lymphoid cells. Nat Commun. 2017 Dec 1;8(1):1900.

Seehus C, Kaye J. In vitro differentiation of murine innate lymphoid cells from common lymphoid progenitor cells. Bio Protoc. 2016 Mar 20;6(6). pii: e1770.

Seehus CR, Aliahmad P, de la Torre B, Iliev ID, Spurka L, Funari VA, Kaye J. The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor. Nat Immunol. 2015 Jun;16(6):599-608.

Seksenyan A, Kadavallore A, Walts AE, de la Torre B, Berel D, Strom SP, Aliahmad P, Funari VA, Kaye J. TOX3 is expressed in mammary ER(+) epithelial cells and regulates ER target genes in luminal breast cancer. BMC Cancer. 2015 Jan 30;15:22.

Aliahmad P, Kadavallore A, de la Torre B, Kappes D, Kaye J. TOX is required for development of the CD4 T cell lineage gene program. J Immunol. 2011;187(11):5931-5940.

Aliahmad P, de la Torre B, Kaye J. Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages. Nat Immunol. 2010 Oct;11(10):945-952.

Aliahmad P, Kaye J. Development of all CD4 T lineages requires nuclear factor TOX. J Exp Med. 2008 Jan 21;205(1):245-256.

O’Flaherty E, Kaye J. TOX defines a conserved subfamily of HMG-box proteins. BMC Genomics. 2003 Apr 2;4(1):13.

Wilkinson B, Chen JY, Han P, Rufner KM, Goularte OD, Kaye J. TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nat. Immunol. 2002 Mar;3(3):272-280.