I have been involved in women's cancer research for more than 10 years. The Lawrenson Laboratory focuses on ovarian cancer and how we can detect ovarian cancers earlier and treat these tumors more effectively. In the Lawrenson Lab, we use a variety of in vitro models, in vivo models, genomic profiling and molecular biology techniques to elucidate the function of variants, genes and noncoding biofeatures involved in ovarian cancer development.
A major goal of my research group is to understand the role of long noncoding RNAs in ovarian cancer biology. Subtype- and subgroup-specific approaches, which are the central theme of this research, will be required to identify new markers and targets that could ultimately be used clinically to reduce morbidity and mortality associated with ovarian carcinoma.