See a complete PubMed list of publications by George Liu, MD, PhD.

Selected Key Publications

Kolar SL, Liu GY. RAS and ROS-A story of pseudomonas survival. Cell Host Microbe. 2017 May 10;21(5):551-552.

Kolar S, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY. Group B Streptococcus evades host immunity by degrading hyaluronan. Cell Host Microbe. 2015;18(6):694-704.

Tseng CW, Biancotti JC, Berg BL, Gate D, Kolar SL, Muller S, Rodriguez MD, Rezai-Zadeh K, Fan X, Beenhouwer DO, Town T, Liu GY. Increased susceptibility of humanized NSG mice to Panton-Valentine leukocidin and Staphylococcus aureus skin infection. PLOS Pathog. 2015;11(11):e1005292.

Sabrina Müller, Wolf AJ, Iliev ID, Berg BL, Underhill DM, Liu GY. Poorly cross-linked peptidoglycan in MRSA due to mecA induction activates the inflammasome and exacerbates immunopathology. Cell Host Microbe. 2015;18(5):604-612.

Tseng CW, Liu GY. Expanding roles of neutrophils in aging hosts. Curr Opin Immunol. 2014 Aug;29:43-48.

Kyme P, Thoennissen NH, Tseng CW, Iwanski GB, Shimada K, Krug UO, Lee K, Hardy WD, Gombart AF, Koeffler HP, Liu GY. C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice. J Clin Invest. 2012;122(9):3316-3329.

Park B, Liu GY. Targeting the host-pathogen interface for treatment of Staphylococcus aureus infection. Sem Immunopath. 2012;34(2):299-315.

Shimada T, Park B, Goodridge HS, Wolf AJ, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation and IL-1beta secretion. Cell Host Microbe. 2010;7(1):38-49.

Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLOS ONE. 2009;4(7):e6837.

Liu GY, Nizet V. Color me bad: microbial pigments as virulence factors. Trends Microbiol. 2009;17(9):406-413.

Liu C-I, Liu GY, Song Y, Yin F, Hensler ME, Nizet V, Wang AH, Oldfield E. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008;319(5868):1391-1394.

Park B, Nizet V, Liu GY. Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae. J Bacteriol. 2008;190(7):2275-2278.

Liu GY, Essex A, Buchanan JT, Datta V, Fierer J, Nizet V. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. J Exp Med. 2005;202(2):209-215.

Liu GY, Doran K, Lawrence T, Turkson N, Puliti M, Tissi L, Nizet V. Sword and shield: linked group B streptococcal β-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense. Proc Natl Acad Sci USA. 2004;101(40):14491-14496.

Liu, GY, Fairchild, PJ, Smith, RM, Prowle, JR, Koussis, D, Wraith, DC. Low avidity recognition of self-antigen by T cells permits escape from central tolerance. Immunity. 1995;3(4):407-415.