Publications

See a complete PubMed list of publications by Alexander Ljubimov, PhD.

Selected Key Publications

Leszczynska A, Kulkarni M, Ljubimov AV, Saghizadeh M. Exosomes from normal and diabetic human corneolimbal keratocytes differentially regulate migration, proliferation and marker expression of limbal epithelial cells. Sci Rep. 2018 Oct 11;8(1):15173. https://www.nature.com/articles/s41598-018-33169-5.

Saghizadeh M, Kramerov AA, Svendsen CN, Ljubimov AV. Concise review: stem cells for corneal wound healing. Stem Cells. 2017 Oct;35(10):2105-2114. https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.1002/stem.2667.

Ljubimova JY, Sun T, Mashouf L, Ljubimov AV, Israel LL, Ljubimov VA, Falahatian V, Holler E. Covalent nano delivery systems for selective imaging and treatment of brain tumors. Adv Drug Deliv Rev. 2017 Apr;113:177-200. https://www.sciencedirect.com/science/article/pii/S0169409X17300868.

Ljubimov AV. Diabetic complications in the cornea. Vision Res. 2017 Oct;139:138-152. https://www.sciencedirect.com/science/article/pii/S0042698917300470.

Ljubimov AV, Saghizadeh M. Progress in corneal wound healing.Prog Retin Eye Res. 2015 Nov;49:17-45. http://www.sciencedirect.com/science/article/pii/S135094621500049X.

Patil R, Ljubimov AV, Gangalum PR, Ding H, Portilla-Arias J, Wagner S, Inoue S, Konda B, Rekechenetskiy A, Chesnokova A, et al. MRI virtual biopsy and treatment of brain metastatic tumors with targeted nanobioconjugates: nanoclinic in the brain. ACS Nano. 2015 May; 26;9(5):5594-5608. http://pubs.acs.org/doi/abs/10.1021/acsnano.5b01872.

Saghizadeh M, Dib CM, Brunken WJ, Ljubimov AV. Normalization of wound healing and stem cell marker patterns in organ-cultured human diabetic corneas by gene therapy of limbal cells. Exp Eye Res. 2014 Dec;129:66-73. http://www.sciencedirect.com/science/article/pii/S0014483514002954.

Sareen D, Saghizadeh M, Ornelas L, Winkler MA, Narwani K, Sahabian A, Funari VA, Tang J, Spurka L, Punj V, Maguen E, Rabinowitz YS, Svendsen CN, Ljubimov AV. Differentiation of human limbal-derived induced pluripotent stem cells into limbal-like epithelium. Stem Cells Transl Med. 2014 Sep;3(9):1002-1012. https://stemcellsjournals.onlinelibrary.wiley.com/doi/10.5966/sctm.2014-0076.

Saghizadeh M, Winkler MA, Kramerov AA, Hemmati DM, Ghiam CA, Dimitrijevich SD, Sareen D, Ornelas L, Ghiasi H, Brunken WJ, Maguen E, Rabinowitz YS, Svendsen CN, Jirsova K, Ljubimov AV. A simple alkaline method for decellularizing human amniotic membrane for cell culture. PLOS One. 2013 Nov 13;8(11):e79632. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079632.

Saghizadeh M, Soleymani S, Harounian A, Bhakta B, Troyanovsky SM, Brunken WJ, Pellegrini G, Ljubimov AV. Alterations of epithelial stem cell marker patterns in human diabetic corneas and effects of c-met gene therapy. Mol Vis. 2011;17:2177-2190. http://www.molvis.org/molvis/v17/a236/.

Saghizadeh M, Kramerov AA, Yu FS, Castro MG, Ljubimov AV. Normalization of wound healing and diabetic markers in organ-cultured human diabetic corneas by adenoviral delivery of c-met gene. Invest Ophthalmol Vis Sci. 2010 Apr;51(4):1970-1980. http://iovs.arvojournals.org/article.aspx?articleid=2185877.

Ding H, Inoue S, Ljubimov AV, Patil R, Portilla-Arias J, Hu J, Konda B, Wawrowsky KA, Fujita M, Karabalin N, et al. Inhibition of brain tumor growth by intravenous poly(b-L-malic acid) nanobioconjugate with pH-dependent drug release. Proc Natl Acad Sci USA. 2010 Oct 19;107(42):18143-18148. http://www.pnas.org/content/107/42/18143.

Kramerov AA, Saghizadeh M, Caballero S, Shaw LC, Li Calzi S, Bretner M, Montenarh M, Pinna LA, Grant MB, Ljubimov AV. Inhibition of protein kinase CK2 suppresses angiogenesis and hematopoietic stem cell recruitment to retinal neovascularization sites. Mol Cell Biochem. 2008 Sep;316(1-2):177-186. https://link.springer.com/article/10.1007/s11010-008-9831-4.

Ljubimova JY, Lakhter AJ, Loksh A, Yong WH, Riedinger MS, Miner JH, Sorokin LM, Ljubimov AV, Black KL. Overexpression of a4 chain-containing laminins in human glial tumors identified by gene microarray analysis. Cancer Res. 2001 Jul;61(14):5601-5610. http://cancerres.aacrjournals.org/content/61/14/5601.

Ljubimov AV, Burgeson RE, Butkowski RJ, Michael AF, Sun T-T, Kenney MC. Human corneal basement membrane heterogeneity: topographical differences in the expression of type IV collagen and laminin isoforms. Lab Invest. 1995;72(4):461-473. http://www.ncbi.nlm.nih.gov/pubmed/7723285.