Research in the Parks Laboratory focuses on the role of matrix metalloproteinases (MMPs) in immunity, tissue repair and fibrosis. With an emphasis on models of lung and skin diseases, the Parks Lab has determined that individual MMPs control distinct, nonoverlapping functions in antimicrobial defense, epithelial repair and differentiation, leukocyte influx and activation, and resolution of fibrosis.
The Parks Laboratory is affiliated with the Women's Guild Lung Institute and the Department of Biomedical Sciences.
Figure 1. Structure of MMPs