See a complete PubMed list of publications by William Parks, PhD.

Selected Key Publications

Rohani MG, Dimitrova E, Beppu A, Wang Y, Jefferies CA, Parks WC. Macrophage MMP10 regulates TLR7-mediated tolerance. Front Immunol. 2018 Dec 4;9:2817.

Smigiel KS, Parks WC. Macrophages, wound healing and fibrosis: recent insights. Curr Rheumat Rep. 2018 Mar 17;20(4):17.

Secor PR, Michaels LA, Smigiel KS, Rohani MG, Jennings LK, Hisert KB, Arrigoni A, Braun KR, Birkland TP, Lai Y, Hallstrand TS, Bollyky PL, Singh PK, Parks WC. Filamentous bacteriophage produced by Pseudomonas aeruginosa alters the inflammatory response and promotes noninvasive infection in vivo. Infect Immun. 2016 Dec 29;85(1). pii: e00648-00616. (Cover article)

McMahan RS, Birkland TP, Smigiel KS, Vandivort TC, Rohani MG, Manicone AM, McGuire JK, Gharib SA, Parks WC. Stromelysin-2 (MMP10) moderates inflammation by controlling macrophage activation. J Immunol. 2016 Aug 1;197(3):899-909.

Gill SE, Nadler ST, Li Q, Park PW, Frevert CW, Chen P, Parks WC. Shedding of syndecan-1/CXCL1 complexes by matrix metalloproteinase 7 functions as an epithelial checkpoint of neutrophil activation. Am J Respir Cell Mol Biol. 2016 Aug;55(2):243-251.

Secor PR, Sweere J, Michaels LA, Malkovskiy AV, Lazzareschi D, Katznelson E, Arrigoni A, Braun KR, Evanko SP, Kaminsky W, Singh PK, Parks WC*, Bollyky PL*. Filamentous bacteriophage promote biofilm assembly and tolerance to desiccation and antibiotics. Cell Host Microbe. 2015;18(5):549-559.

Rohani MG, McMahan RS, Razumova MV, Hertz AL, Cieslewicz M, Pun SH, Regnier M, Wang Y, Birkland TP, Parks WC. MMP-10 regulates collagenolytic activity of alternatively activated resident macrophages. J Invest Dermatol. 2015;135(10):2377-2384.

Gharib SA, Johnston LK, Huizar I, Birkland TP, Hanson J, Wang Y, Parks WC, Manicone AM. MMP28 promotes macrophage polarization toward M2 cells and pulmonary fibrosis. J Leukoc Biol. 2014;95(1):9-18.

Parks WC, Wilson CL, López-Boado YS. Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol. 2004;4(8):617-629.

Li Q, Park PW, Wilson CL, Parks WC. Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury. Cell. 2002;111(5):635-646.