The Perez Laboratory conducts research on the design of nanoparticle technologies with applications in medicine, particularly imaging, diagnostics and therapy. Our main focus is to design clinical translational nanotechnologies for the imaging and treatment of cancer (prostate, breast and brain) as well as neurological diseases such as Alzheimer's disease. In particular, the design of biodegradable and biocompatible nanoparticles with dual imaging and therapeutic capabilities is a major focus of the Perez Lab. Another emphasis of our research group is to discover nanoparticle-based techniques that can be used to interrogate biological systems in the pursuit of novel targets and therapeutics.
Specific areas of research in the Perez Lab are:
- Hyperbranched polymeric nanoparticles as delivery vehicles for imaging and therapeutic agents
- Activatable molecular imaging agents and iron oxide nanoparticle-based delivery agents
- Small-molecule-based activatable prodrugs for the detection and treatment of tumors
- Binding magnetic relaxation nanosensors for the assessment of molecular interactions
The Perez Laboratory is affiliated with the Biomedical Imaging Research Institute, Department of Biomedical Sciences, Nanomedicine Research Center, Neurosurgery Department and the Samuel Oschin Comprehensive Cancer Institute.