See a complete PubMed list of publications by Prediman Krishan (P. K.) Shah, MD.

Selected Key Publications

Honjo T, Chyu KY, Dimayuga PC, Yano J, Lio WM, Trinidad P, Zhao X, Zhou J, Chen S, Cercek B, Arditi M, Shah PK. ApoB-100-related peptide vaccine protects against angiotensin II-induced aortic aneurysm formation and rupture. J Am Coll Cardiol. 2015 Feb 17;65(6):546-556.

Shah PK, Chyu KY, Dimayuga PC, Nilsson J. Vaccine for atherosclerosis. J Am Coll Cardiol. 2014 Dec 30;64(25):2779-2791.

Tian F, Wang L, Arias A, Yang M, Sharifi BG, Shah PK. Comparative antiatherogenic effects of intravenous AAV8- and AAV2-mediated ApoA-I Milano gene transfer in hypercholesterolemic mice. J Cardiovasc Pharmacol Ther. 2015 Jan;20(1):66-75.

Wang L, Shah PK, Wang W, Song L, Yang M, Sharifi BG. Tenascin-C deficiency in ApoE-/- mouse increases eotaxin levels: implications for atherosclerosis. Atherosclerosis 2013 Apr;227(2):267-274.

Wang L, Wang W, Shah PK, Song L, Yang M, Sharifi BG. Deletion of tenascin-C gene exacerbates atherosclerosis and induces intraplaque hemorrhage in ApoE-deficient mice. Cardiovasc Pathol. 2012 Sep-Oct;21(5):398-413.

Chyu KY, Zhao X, Dimayuga PC, Zhou J, Li X, Yano J, Lio WM, Chan LF, Kirzner J, Trinidad P, Cercek B, Shah PK. CD8+ T cells mediate the athero-protective effect of immunization with an ApoB-100 peptide. PLOS One 2012;7(2):e30780.

Schiopu A, Frendéus B, Jansson B, Söderberg I, Ljungcrantz I, Araya Z, Shah PK, Carlsson R, Nilsson J, Fredrikson GN. Recombinant antibodies to an oxidized low-density lipoprotein epitope induce rapid regression of atherosclerosis in apobec-1(-/-)/low-density lipoprotein receptor(-/-) mice. J Am Coll Cardiol. 2007 Dec 11;50(24):2313-2318.

Wang L, Sharifi BG, Pan T, Song L, Yukht A, Shah PK. Bone marrow transplantation shows superior atheroprotective effects of gene therapy with apolipoprotein A-I Milano compared with wild-type apolipoprotein A-I in hyperlipidemic mice. J Am Coll Cardiol. 2006 Oct 3;48(7):1459-1468.

Sharifi BG, Zeng Z, Wang L, Song L, Chen H, Qin M, Sierra-Honigmann MR, Wachsmann-Hogiu S, Shah PK. Pleiotrophin induces transdifferentiation of monocytes into functional endothelial cells. Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1273-1280.

Chyu KY, Zhao X, Reyes OS, Babbidge SM, Dimayuga PC, Yano J, Cercek B, Fredrikson GN, Nilsson J, Shah PK. Immunization using an ApoB-100 related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic ApoE (-/-) mice. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1982-1989.

Kaul S, Coin B, Hedayiti A, Yano J, Cercek B, Chyu KY, Shah PK. Rapid reversal of endothelial dysfunction in hypercholesterolemic apolipoprotein E-null mice by recombinant apolipoprotein A-I(Milano)-phospholipid complex. J Am Coll Cardiol. 2004 Sep 15;44(6):1311-1319.

Michelsen KS, Wong MH, Shah PK, Zhang W, Yano J, Doherty TM, Akira S, Rajavashisth TB, Arditi M. Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10679-10684.

Kaul S, Rukshin V, Santos R, Azarbal B, Bisgaier CL, Johansson J, Tsang VT, Chyu KY, Cercek B, Mirocha J, Shah PK. Intramural delivery of recombinant apolipoprotein A-I Milano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries. Circulation 2003 May 27;107(20):2551-2554.

Fredrikson GN, Söderberg I, Lindholm M, Dimayuga P, Chyu KY, Shah PK, Nilsson J. Inhibition of atherosclerosis in ApoE-null mice by immunization with ApoB-100 peptide sequences. Arterioscler Thromb Vasc Biol. 2003 May 1;23(5):879-884.;23/5/879.

Qin M, Zeng Z, Zheng J, Shah PK, Schwartz SM, Adams LD, Sharifi BG. Suppression subtractive hybridization identifies distinctive expression markers for coronary and internal mammary arteries. Arterioscler Thromb Vasc Biol. 2003 Mar 1;23(3):425-433.