Publications

See a complete PubMed list of publications by Robin Shaw, MD, PhD.

Selected Key Publications

Xie Y, Hitzeman TC, Zadikany RH, Nikolova AP, Baum R, Xu B, Agvanian S, Melmed GY, McGovern DT, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong TT, Shaw RM. Plasma cBIN1 score (CS) identifies HFrEF and can predict cardiac hospitalization in stable ambulatory patients. Preprints. Online January 7, 2018. https://www.preprints.org/manuscript/201801.0040/v1.

Nikolova AP, Hitzeman TC, Baum R, Xu B, Agvanian S, Xie Y, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong TT, Shaw RM. Plasma cBIN1 score (CS) identifies HFpEF and can predict cardiac hospitalization in stable ambulatory patients. Preprints. Online January 7, 2018. https://www.preprints.org/manuscript/201801.0041/v1.

Basheer WA, Xiao S, Epifantseva I, Fu Y, Kleber AG, Hong TT, Shaw RM. GJA1-20k arranges actin to guide Cx43 delivery to cardiac intercalated discs. Circ Res. 2017 Oct 13;121(9):1069-1080. http://circres.ahajournals.org/content/121/9/1069.

Fu Y, Zhang SS, Xiao S, Basheer WA, Baum R, Epifantseva I, Hong T, Shaw RM. Cx43 isoform GJA1-20k promotes microtubule dependent mitochondrial transport. Front Physiol. 2017 Nov 7;8:905. https://www.frontiersin.org/articles/10.3389/fphys.2017.00905/full.

Xu B, Fu Y, Liu Y, Agvanian S, Wirka RC, Baum R, Zhou K, Shaw RM, Hong T. The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles. PLoS Biol. 2017 Aug 14;15(8):e2002354. http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2002354.

Hong T, Shaw RM. Cardiac T-tubule microanatomy and function. Physiol Rev. 2017 Jan; 97:227-252. http://www.physiology.org/doi/full/10.1152/physrev.00037.2015.

Epifantseva I, Shaw RM. Intracellular trafficking pathways of Cx43 gap junction channels. Biochim Biophys Acta. 2018 Jan; 1860(1):40-47. https://www.sciencedirect.com/science/article/pii/S0005273617301797.

Hong T, Yang H, Zhang S, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014 Jun;20(6):624-632. http://www.nature.com/nm/journal/v20/n6/full/nm.3543.html.

Smyth JW, Zhang SS, Sanchez JM, Lamouille S, Vogan JM, Hesketh GG, Hong T, Tomaselli GF, Shaw RM. A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia. Traffic. 2014 June;15(6):684-699. http://onlinelibrary.wiley.com/doi/10.1111/tra.12169/full.

Smyth JW, Shaw RM. Autoregulation of connexin43 gap junction formation by internally translated isoforms. Cell Rep. 2013 Nov 14;5(3):611-618. http://www.cell.com/cell-reports/abstract/S2211-1247(13)00578-0.

Smyth JW, Vogan JM, Buch PJ, Zhang SS, Fong TS, Hong TT, Shaw RM. Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res. 2012 Mar 30;110(7):978-989. http://circres.ahajournals.org/content/110/7/978.

Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, DeMarco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012 Jun;9(6):961-967. http://www.heartrhythmjournal.com/article/S1547-5271(12)00083-5/abstract.

Hong TT, Smyth JW, Chu K, Vogan J, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012 May;9(5):812-820. http://www.heartrhythmjournal.com/article/S1547-5271(11)01455-X/abstract.

Hong TT, Smyth JW, Gao D, Chu K, Vogan J, Fong TS, Jensen BC, Colecraft, H, Shaw RM. BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol. 2010 Feb 16;8(2):e1000312. http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1000312.

Smyth JW, Hong TT, Gao D, Vogan J, Jensen BC, Fong TS, Simpson PC, Stainier DY, Chi NC, Shaw RM. Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest. 2010 Jan;120(1):266-279. http://www.jci.org/articles/view/39740.