Current research in the Slomka Laboratory focuses on developing novel methods for fully automated analysis of nuclear cardiology data using novel algorithms and machine learning techniques, and on the development of integrated motion-corrected analysis of positron emission tomography (PET)/computed tomography (CT) angiography imaging.
Research in the Slomka Laboratory is supported by the National Heart, Lung and Blood Institute at the National Institutes of Health.
This research was originally published in the Journal of Nuclear Medicine. Rubeaux M, Joshi NV, Dweck MR, Fletcher A, Motwani M, Thomson LE, Germano G, Dey D, Li D, Berman DS, Newby DE, Slomka PJ. Motion correction of 18F-NaF PET for imaging coronary atherosclerotic plaques. J Nucl Med. 2016;57(1):54-59. http://jnm.snmjournals.org/content/57/1/54.full. © by the Society of Nuclear Medicine and Molecular Imaging, Inc.
The figure above shows noise decrease and target-to-background ratio improvement in 18F-sodium fluoride PET images displaying a 3-D rendering of end-diastolic image (left) and a motion-corrected image (right) superimposed on CT angiography 3-D rendering. Increased uptake is seen in all coronary arteries, but it is difficult to differentiate from the noise in the end-diastolic image and becomes clearly visible in the motion-corrected image.