Publications

See a complete PubMed list of publications by Christopher J. Wheeler, PhD.

Selected Key Publications


Junes-Gill KS, Lawrence CE, Wheeler CJ, Cordner R, Gill TG, Mar V, Shiri L, Basile LA. Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis. BMC Cancer. 2014 Dec 6;14:920. https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-920.

Wheeler CJ, Seksenyan A, Koronyo Y, Rentsendorj A, Sarayba D, Wu H, Gragg A, Siegel E, Thomas D, Espinosa A, et al. T-lymphocyte deficiency exacerbates behavioral deficits in the 6-OHDA unilateral lesion rat model for Parkinson's disease. J Neurol Neurophysiol. 2014 May;5(3). pii: 209. http://www.omicsonline.org/open-access/tlymphocyte-deficiency-exacerbates-behavioral-deficits-in-the-ohda-unilateral-lesion-rat-model-for-parkinsons-disease-2155-9562-5-1000209.php?aid=26665.

Jouanneau E, Black KL, Veiga L, Cordner R, Goverdhana S, Zhai Y, Zhang XX, Panwar A, Mardiros A, Wang H, Gragg A, Zandian M, Irvin DK, Wheeler CJ. Intrinsically de-sialylated CD103(+) CD8 T cells mediate beneficial anti-glioma immune responses. Cancer Immunol Immunother. 2014 Sep;63(9):911-924. http://link.springer.com/article/10.1007%2Fs00262-014-1559-2.

Phuphanich S, Wheeler CJ, Rudnick JD, Mazer M, Wang H, Nuño MA, Richardson JE, Fan X, Ji J, Chu RM, et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother. 2013 Jan;62(1):125-135. http://link.springer.com/article/10.1007%2Fs00262-012-1319-0.

Irvin DK, Jouanneau E, Duvall G, Zhang XX, Zhai Y, Sarayba D, Seksenyan A, Panwar A, Black KL, Wheeler CJ. T cells enhance stem-like properties and conditional malignancy in gliomas. PLOS One 2010 Jun 7;5(6):e10974. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010974.

Wheeler CJ, Das A, Liu G, Yu JS, Black KL. Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination. Clin Cancer Res. 2004 Aug 15;10(16):5316-5326. http://clincancerres.aacrjournals.org/content/10/16/5316.short.

Wheeler CJ, Yu JS, Black KL. Cellular immunity in the treatment of brain tumors. Clin Neurosurg. 2004;51:132-139. No abstract available.

Yu JS, Liu G, Ying H, Yong WH, Black KL, Wheeler CJ. Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma. Cancer Res. 2004 Jul;64(14):4973-4979. http://cancerres.aacrjournals.org/content/64/14/4973.short.

Prins RM, Incardona F, Lau R, Lee P, Claus S, Zhang W, Black KL, Wheeler CJ. Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity. J Immunol. 2004 Feb 1;172(3):1602-1611. http://www.jimmunol.org/content/172/3/1602.short.

Wheeler CJ, Black KL, Liu G, Ying H, Yu JS, Zhang W, Lee PK. Thymic CD8+ T cell production strongly influences tumor antigen recognition and age-dependent glioma mortality. J Immunol. 2003 Nov 1;171(9):4927-4933. http://www.jimmunol.org/content/171/9/4927.full.pdf.

Prins RM, Graf MR, Merchant RE, Black KL, Wheeler CJ.
Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression. J Neurooncol. 2003 Aug-Sep;64(1-2):45-54. http://link.springer.com/article/10.1023%2FA%3A1024929724736.

Yu JS, Lee PK, Ehtesham M, Samoto K, Black KL, Wheeler CJ. Intratumoral T cell subset ratios and Fas ligand expression on brain tumor endothelium. J Neurooncol. 2003 Aug-Sep;64(1-2):55-61. http://link.springer.com/article/10.1007/BF02700020.

Wheeler CJ, von Hoegen P, Parnes JR. An immunological role for the CD8 β-chain. Nature 1992 May 21;357:247-249. http://www.nature.com/nature/journal/v357/n6375/abs/357247a0.html.

Wheeler CJ, Maloney D, Fogel S, Goodenow RS. Microconversion between murine H-2 genes integrated into yeast. Nature 1990 Sep 13;347:192-194. http://www.nature.com/nature/journal/v347/n6289/abs/347192a0.html.