Center for Bioinformatics and Functional Genomics
The Cedars-Sinai Center for Bioinformatics and Functional Genomics (CBFG) is an integrated, interdisciplinary research group established in 2016, with the common goal of developing end-to-end research workflows for genomic and high-throughput functional analysis of patient samples. Led by director, Simon Gayther, PhD, the primary goals of the CBFG are to establish a research nexus that integrates leading-edge developments in computational sciences, next-generation genomics and epigenomics, and to use functional biology to improve our understanding of disease etiology applied to personalized health.
Preventing the Spread of Deadly Breast Cancer
Researchers have found that limiting asparagine in the diet could reduce cancer’s ability to spread.
Director
What genetics is doing is allowing us to imagine a future in which, based on individual screening, we can give a patient actionable advice."
Simon Gayther, PhD
Barth Family Chair in Cancer Genetics in honor of Beth Y. Karlan, MD
Director, Molecular Epidemiology
Director, Center for Bioinformatics and Functional Genomics
Research Laboratories
Our laboratories form an integrated, interdisciplinary research group solving vexing problems and discovering new treatments.
Research in the Gayther Laboratory focuses on the discovery of genetic variants using next-generation sequencing and genotyping technologies.
The Hazelett Laboratory is working to understand how genetic variation contributes to disease etiology.
The Hitchins Laboratory undertakes translational cancer research with a focus on genetic and epigenetic alterations associated with cancer, in particular cancer-specific changes in DNA methylation.
The goal of the Knott Laboratory is to develop cancer treatment strategies that are focused on the hetero-cellular interactions within tumors that drive disease progression.
Job Openings
Project Scientist (Knott Laboratory)
The Knott laboratory at Cedars-Sinai Medical Center is searching for a Project Scientist with a strong background in tumor biology and the immune microenvironment to lead single cell-based omics studies of immunotherapy clinical trials being carried out at the medical center. The scientist will manage a team of laboratory technicians through the processing of clinical trial biopsies for profiling with single cell RNA and ATAC sequencing as well as other emerging technologies. Learn more and apply now.
Have Questions or Need Help?
Contact us if you have questions, or wish to learn more about bioinformatics and functional genomics research at Cedars-Sinai.
Spielberg
8723 Alden Drive, Suite 100
Los Angeles, CA 90048